Literature DB >> 24427624

Laryngeal paraganglioma: a rare clinical entity managed by supraselective embolization and lateral pharygotomy.

Sudhir M Naik1, Ashok M Shenoy1, Purshottam Chavan1, Akkamahadevi Patil2, Sumit Gupta1.   

Abstract

Laryngeal paragangliomas are benign slow growing tumors with symptoms resembling squamous cell carcinoma. Hoarseness or dysphasia are the commonest presenting symptoms and usually it presents as an submucosal mass on laryngoscopy. Ninety percentage of these tumors occur in the supraglottic larynx and the rest in the glottis and the subglottic region. Functional activity is seen in a few (2.9 %), none are associated with paraneoplastic syndromes. A 35-year-old male presented to us with hoarseness of voice since 4 months duration. Contrast arteriography demonstrated that the left superior thyroid artery supplied >80 % of the blood supply to the laryngeal mass. Supraselective embolization was done from the right femorals under local anaesthesia and sedation which was uneventfull. The tumor was excised from lateral pharyngotomy approach with an partial laryngectomy procedure. Microscopy and immune-histochemistry confirmed it to be paraganglioma. Complete surgical resection or partial laryngectomy with meticulous dissection of surrounding tissues and preservation of neurovascular structures gives an excellent prognosis as far as oncological clearance is concerned. Malignant paragangliomas of the larynx are rare and an major meta-analysis is necessary to provide a true biological behaviour of this tumor.

Entities:  

Keywords:  Digital substraction angiography; Embolization; Lateral pharygotomy; Paraganglioma

Year:  2012        PMID: 24427624      PMCID: PMC3718947          DOI: 10.1007/s12070-012-0575-9

Source DB:  PubMed          Journal:  Indian J Otolaryngol Head Neck Surg        ISSN: 2231-3796


  35 in total

Review 1.  Radiographic evaluation and assessment of paragangliomas.

Authors:  E S Lustrin; C Palestro; K Vaheesan
Journal:  Otolaryngol Clin North Am       Date:  2001-10       Impact factor: 3.346

2.  Chemodectoma of the larynx; case report.

Authors:  C L BLANCHARD; W H SAUNDERS
Journal:  AMA Arch Otolaryngol       Date:  1955-04

Review 3.  Review: Should patients with apparently sporadic pheochromocytomas or paragangliomas be screened for hereditary syndromes?

Authors:  Camilo Jiménez; Gilbert Cote; Andrew Arnold; Robert F Gagel
Journal:  J Clin Endocrinol Metab       Date:  2006-05-30       Impact factor: 5.958

Review 4.  Laryngeal paraganglioma: an updated critical review.

Authors:  David Myssiorek; Alessandra Rinaldo; Leon Barnes; Alfio Ferlito
Journal:  Acta Otolaryngol       Date:  2004-11       Impact factor: 1.494

5.  Diagnosis and treatment of supraglottic laryngeal paraganglioma: report of a case.

Authors:  John M Del Gaudio; Susan Muller
Journal:  Head Neck       Date:  2004-01       Impact factor: 3.147

6.  Paragangliomas of the head and neck. Immunohistochemical analysis of 16 cases in comparison with neuro-endocrine carcinomas.

Authors:  F Martinez-Madrigal; J Bosq; C Micheau; P Nivet; B Luboinski
Journal:  Pathol Res Pract       Date:  1991-09       Impact factor: 3.250

7.  Neuroendocrine tumors of larynx.

Authors:  J G Batsakis; A K el-Naggar; M A Luna
Journal:  Ann Otol Rhinol Laryngol       Date:  1992-08       Impact factor: 1.547

Review 8.  Laryngeal paraganglioma versus atypical carcinoid tumor.

Authors:  A Ferlito; C M Milroy; B M Wenig; L Barnes; C E Silver
Journal:  Ann Otol Rhinol Laryngol       Date:  1995-01       Impact factor: 1.547

9.  Paragangliomas of the neck.

Authors:  G B Bishop; M M Urist; T el Gammal; G E Peters; W A Maddox
Journal:  Arch Surg       Date:  1992-12

10.  MRI screening of kindred at risk of developing paragangliomas: support for genomic imprinting in hereditary glomus tumours.

Authors:  A P van Gils; A G van der Mey; R P Hoogma; L A Sandkuijl; P D Maaswinkel-Mooy; T H Falke; E K Pauwels
Journal:  Br J Cancer       Date:  1992-06       Impact factor: 7.640

View more
  1 in total

1.  Operative technique in laryngeal paraganglioma: A case series and literature review.

Authors:  Saikrishna Ananthapadmanabhan; Joe Jabbour; Evangelos Tseros; Vanaja Sivapathasingam; Mark Smith; Faruque Riffat; Niranjan Sritharan
Journal:  Laryngoscope Investig Otolaryngol       Date:  2022-02-15
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.