Literature DB >> 24427088

1',1''-Dimethyl-4'-(4-methyl-phen-yl)di-spiro-[11H-indeno-[1,2-b]quinoxaline-11,2'-pyrrolidine-3',3''-piperidin]-4''-one.

R A Nagalakshmi1, J Suresh1, K Malathi2, R Ranjith Kumar2, P L N Lakshman3.   

Abstract

In the title compound, C31H30N4O, the central pyrrolidine ring adopts an envelope conformation with the methyl-ene C atom being the flap. The quinoxaline and indane rings are each planar, having r.m.s. deviations of 0.030 and 0.050 Å, respectively. The pyrrolidine ring mean plane forms dihedral angles of 88.25 (1) and 83.76 (1)° with the quinoxaline and indane rings, respectively. Intra-molecular C-H⋯O and C-H⋯N inter-actions are observed. In the crystal, C-H⋯π inter-actions lead to helical supra-molecular chains along the b-axis direction.

Entities:  

Year:  2013        PMID: 24427088      PMCID: PMC3884467          DOI: 10.1107/S1600536813022964

Source DB:  PubMed          Journal:  Acta Crystallogr Sect E Struct Rep Online        ISSN: 1600-5368


  4 in total

1.  A short history of SHELX.

Authors:  George M Sheldrick
Journal:  Acta Crystallogr A       Date:  2007-12-21       Impact factor: 2.290

2.  Synthesis and biological evaluation of certain alpha,beta-unsaturated ketones and their corresponding fused pyridines as antiviral and cytotoxic agents.

Authors:  H I El-Subbagh; S M Abu-Zaid; M A Mahran; F A Badria; A M Al-Obaid
Journal:  J Med Chem       Date:  2000-07-27       Impact factor: 7.446

3.  A conformational and structure-activity relationship study of cytotoxic 3,5-bis(arylidene)-4-piperidones and related N-acryloyl analogues.

Authors:  J R Dimmock; M P Padmanilayam; R N Puthucode; A J Nazarali; N L Motaganahalli; G A Zello; J W Quail; E O Oloo; H B Kraatz; J S Prisciak; T M Allen; C L Santos; J Balzarini; E De Clercq; E K Manavathu
Journal:  J Med Chem       Date:  2001-02-15       Impact factor: 7.446

4.  Structure validation in chemical crystallography.

Authors:  Anthony L Spek
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2009-01-20
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.