Literature DB >> 24426766

Burned out seminomatous testicular tumor with retroperitoneal lymph node metastasis: a case report.

Pradyumna Kumar Sahoo1, Palash Kumar Mandal2, Supti Mukhopadhyay2, Samindra Nath Basak3.   

Abstract

Germ cell tumor is the most common malignancy in men aged 15-35 years. About five percent of the malignant germ cell tumors are extragonadal in origin. However metastatic deposit of seminoma in retroperitoneal lymph node without presence of any tumor in the testes is uncommon. We present a case of metastatic retroperitoneal seminoma as the initial presentation of a burned out testicular primary. The patient presented with pain in abdomen and back. Ultrasonography of the testis showed a lesion, which after high inguinal ochidectomy was reported as fibrosis only, without any tumor, i.e. burned out phenomenon. A laparotomy biopsy of the retroperitoneal lymph node mass was taken and reported as metastatic seminoma after immunohistochemistry. After 14 months of chemotherapy there is a residual lymph node of less than 3cm, serum tumor markers are normal and the patient is under observation.

Entities:  

Keywords:  Burned out phenomenon; Extragonadal germ cell tumor; Seminoma; Testis

Year:  2013        PMID: 24426766      PMCID: PMC3890024          DOI: 10.1007/s13193-012-0207-6

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  7 in total

Review 1.  Extragonadal germ cell tumors.

Authors:  H-J Schmoll
Journal:  Ann Oncol       Date:  2002       Impact factor: 32.976

2.  Retroperitoneal seminoma with 'burned out' phenomenon in the testis.

Authors:  Petros Perimenis; Anastasios Athanasopoulos; John Geraghty; Ru Macdonagh
Journal:  Int J Urol       Date:  2005-01       Impact factor: 3.369

3.  Extragonadal retroperitoneal germ cell tumor: evidence of origin in the testis.

Authors:  M Scholz; M Zehender; G N Thalmann; M Borner; H Thöni; U E Studer
Journal:  Ann Oncol       Date:  2002-01       Impact factor: 32.976

4.  Metastases of clinically occult testicular seminoma mimicking primary extragonadal retroperitoneal germ cell tumors.

Authors:  B Coulier; Y Lefebvre; L de Visscher; A Bourgeois; L Montfort; M Clausse; P Mailleux; I Gielen
Journal:  JBR-BTR       Date:  2008 Jul-Aug

5.  Burned-out testicular tumor: a case report.

Authors:  N Balalaa; M Selman; W Hassen
Journal:  Case Rep Oncol       Date:  2011-01-15

6.  Burned-out testicular tumor with retroperitoneal lymph node metastasis: a case report.

Authors:  Stylianos Kontos; Grigorios Doumanis; Maria Karagianni; Vasilios Politis; Vasileios Simaioforidis; Stefanos Kachrilas; Sotirios Koritsiadis
Journal:  J Med Case Rep       Date:  2009-07-31

7.  Burned-out testis tumour that metastasized to retroperitoneal lymph nodes: a case report.

Authors:  Mehmet Yucel; Sahin Kabay; Ugur Saracoglu; Soner Yalcinkaya; Namik Kemal Hatipoglu; Erol Aras
Journal:  J Med Case Rep       Date:  2009-05-29
  7 in total
  3 in total

1.  Spontaneous gas in a retroperitoneal mass: check the testis!

Authors:  Jérémy Dana; Florian Maxwell; David Eiss; Laurence Rocher
Journal:  Int Braz J Urol       Date:  2019 Jul-Aug       Impact factor: 1.541

2.  A Coculture Model Mimicking the Tumor Microenvironment Unveils Mutual Interactions between Immune Cell Subtypes and the Human Seminoma Cell Line TCam-2.

Authors:  Fabian A Gayer; Alexander Fichtner; Tobias J Legler; Holger M Reichardt
Journal:  Cells       Date:  2022-03-04       Impact factor: 6.600

3.  Brain Metastases as Presenting Feature in 'Burned Out' Testicular Germ Cell Tumor.

Authors:  Kate Johnson; Bryan Brunet
Journal:  Cureus       Date:  2016-04-01
  3 in total

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