Literature DB >> 24426746

L-asparginase induced pseudopancreatic cyst: a rare case report.

S M Abhayakumar1, Samit Purohit2, B S Arunakumari3, K C Lakshmaiah4, L Appaji3.   

Abstract

L-Asparginase is a frequently used drug in hematological malignancies. Various side effects associated with its use include hypersensitivity, hyperglycemia, hypercoaguability and acute pancreatitis. We describe a rare complication of pancreatic pseudocyst in a 12 year old boy of Acute lymphoblastic leukemia (ALL) treated with MCP-841 protocol (during re-induction phase). Nearing the end of induction i.e. day 25, patient complained of a painful swelling in the epigastrium and left hypochondrium. Investigations revealed a pancreatic pseudocyst for which he underwent cystojejunostomy. Post surgical period was uneventful.

Entities:  

Keywords:  Acute lymphoblastic leukemia; Cystojejunostomy; L-Asparginase; Pseudopancreatic cyst

Year:  2013        PMID: 24426746      PMCID: PMC3771049          DOI: 10.1007/s13193-013-0250-y

Source DB:  PubMed          Journal:  Indian J Surg Oncol        ISSN: 0975-7651


  14 in total

1.  Pancreatic pseudocyst complicating treatment of acute lymphoblastic leukemia.

Authors:  Sanjay Tomar; Sameer Bakhshi; S K Kabra; L S Arya
Journal:  Indian Pediatr       Date:  2003-07       Impact factor: 1.411

Review 2.  Current management of pancreatic pseudocysts.

Authors:  Betty J Tsuei; Richard W Schwartz
Journal:  Curr Surg       Date:  2003 Nov-Dec

3.  Surgical pancreatic complications induced by L-asparaginase.

Authors:  J Sadoff; S Hwang; D Rosenfeld; L Ettinger; N Spigland
Journal:  J Pediatr Surg       Date:  1997-06       Impact factor: 2.545

4.  L-asparaginase: therapeutic and toxic effects in patients with neoplastic disease.

Authors:  C M Haskell; G P Canellos; B G Leventhal; P P Carbone; J B Block; A A Serpick; O S Selawry
Journal:  N Engl J Med       Date:  1969-11-06       Impact factor: 91.245

5.  Conservative treatment as an option in the management of pancreatic pseudocyst.

Authors:  C V N Cheruvu; M G Clarke; M Prentice; I A Eyre-Brook
Journal:  Ann R Coll Surg Engl       Date:  2003-09       Impact factor: 1.891

6.  Conservative management of pancreatic pseudocysts in children with acute lymphoblastic leukemia.

Authors:  Holly L Spraker; Georgios P Spyridis; Ching-Hon Pui; Scott C Howard
Journal:  J Pediatr Hematol Oncol       Date:  2009-12       Impact factor: 1.289

7.  Pancreatic pseudocyst complicating treatment of acute lymphoblastic leukemia.

Authors:  D A Caniano; A F Browne; E T Boles
Journal:  J Pediatr Surg       Date:  1985-08       Impact factor: 2.545

Review 8.  L-asparaginase-related pancreatic pseudocyst: report of a case.

Authors:  C H Yu; K H Lin; D T Lin; R L Chen; Y C Horng; M H Chang
Journal:  J Formos Med Assoc       Date:  1994-05       Impact factor: 3.282

9.  Timing of surgical drainage for pancreatic pseudocyst. Clinical and chemical criteria.

Authors:  A L Warshaw; D W Rattner
Journal:  Ann Surg       Date:  1985-12       Impact factor: 12.969

10.  Delayed pancreatic pseudocyst formations. Long-term complication of L-asparaginase treatment.

Authors:  S J Bertolone; M M Fuenfer; D B Groff; C C Patel
Journal:  Cancer       Date:  1982-12-15       Impact factor: 6.860

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