Literature DB >> 24426355

Falciparum malaria infection in a case of sickle cell trait; unbalancing the balanced polymorphism.

Amar Amale1, Sourya Acharya1, Samarth Shukla1, Sameeksha Dubey1.   

Abstract

Suffers of Sickle cell trait are protected against plasmodium falciparum malaria because of the law of balanced polymorphism. We present a case of sickle cell trait infected with severe falciparum malaria unbalancing of balanced polymorphism.

Entities:  

Keywords:  Balanced polymorphism; Malaria; Sickle cell trait

Year:  2012        PMID： 24426355      PMCID： PMC3636349          DOI： 10.1007/s12288-012-0158-7

Source DB:  PubMed          Journal:  Indian J Hematol Blood Transfus        ISSN： 0971-4502            Impact factor:   0.900


  7 in total

1.  The sickle-cell and haemoglobin C genes in some African populations.

Authors:  A C ALLISON
Journal:  Ann Hum Genet       Date:  1956-07       Impact factor: 1.670

2.  Exercise and hypoxia increase sickling in venous blood from an exercising limb in individuals with sickle cell trait.

Authors:  T W Martin; I M Weisman; R J Zeballos; S R Stephenson
Journal:  Am J Med       Date:  1989-07       Impact factor: 4.965

3.  Increased sickling of parasitised erythrocytes as mechanism of resistance against malaria in the sickle-cell trait.

Authors:  L Luzzatto; E S Nwachuku-Jarrett; S Reddy
Journal:  Lancet       Date:  1970-02-14       Impact factor: 79.321

Review 4.  Three decades of innovation in the management of sickle cell disease: the road to understanding the sickle cell disease clinical phenotype.

Authors:  Duane Robina Bonds
Journal:  Blood Rev       Date:  2005-03       Impact factor: 8.250

5.  Sickle cell trait and the risk of Plasmodium falciparum malaria and other childhood diseases.

Authors:  Thomas N Williams; Tabitha W Mwangi; Sammy Wambua; Neal D Alexander; Moses Kortok; Robert W Snow; Kevin Marsh
Journal:  J Infect Dis       Date:  2005-05-31       Impact factor: 5.226

6.  Types of anaemic crises in paediatric patients with sickle cell anaemia seen in Enugu, Nigeria.

Authors:  A I Juwah; E U Nlemadim; W Kaine
Journal:  Arch Dis Child       Date:  2004-06       Impact factor: 3.791

Review 7.  The presentation, management and prevention of crisis in sickle cell disease in Africa.

Authors:  A F Fleming
Journal:  Blood Rev       Date:  1989-03       Impact factor: 8.250
  7 in total

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