α-Glucosidase synthesis in batch and continuous culture ofSaccharomyces cerevisiae.

Glucose prevented maltose utilization in batch culture ofSaccharomyces cerevisiae whereas in a mixed carbohydrate-limited system, maltose and glucose were consumed simultaneously. The specific activity of α-glucosidase depended on the dilution rate as well as the proportion of maltose in the mixture. The chemostat provides a way of reaching the low residual concentrations of glucose in the broth that are necessary to release catabolite repression and permit maltose induction of α-glucosidase.