Literature DB >> 24424170

Idiopathic aplastic anemia: diagnosis and classification.

Osnat Jarchowsky Dolberg1, Yair Levy2.   

Abstract

Aplastic anemia (AA) is a disease characterized by pancytopenia and hypoplastic bone marrow caused by the decrease of hematopoietic stem cells. The pathogenesis of AA is complex and involves an abnormal hematopoietic microenvironment, hematopoietic stem cell/progenitor cell deficiencies and immunity disorders. Survival in severe aplastic anemia (SAA) has markedly improved in the past 4 decades because of advances in hematopoietic stem cell transplantation, immunosuppressive and biologic drugs, and supportive care. Herein, we will update the main issues concern AA according to our literature review.
Copyright © 2014 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Aplastic anemia; Autoimmunity; Immunosuppressive therapy; Pancytopenia

Mesh：

Substances：

Year:  2014        PMID： 24424170     DOI： 10.1016/j.autrev.2014.01.014

Source DB:  PubMed          Journal:  Autoimmun Rev        ISSN： 1568-9972            Impact factor:   9.754


  16 in total

1.  CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model of aplastic anemia.

Authors:  Christina Arieta Kuksin; Gabriela Gonzalez-Perez; Lisa M Minter
Journal:  Blood       Date:  2015-02-03       Impact factor: 22.113

Review 2.  Biology of BM failure syndromes: role of microenvironment and niches.

Authors:  Sophia R Balderman; Laura M Calvi
Journal:  Hematology Am Soc Hematol Educ Program       Date:  2014-11-18

3.  Therapeutic effect of androgen therapy in a mouse model of aplastic anemia produced by short telomeres.

Authors:  Christian Bär; Nicolas Huber; Fabian Beier; Maria A Blasco
Journal:  Haematologica       Date:  2015-07-23       Impact factor: 9.941

4.  A New Immunosuppressive Therapy for Very Severe Aplastic Anemia in Children with Autoantibodies.

Authors:  Zhong-Jian Wang; Hong-Bo Chen; Fen Zhou; Hui Yu; Xiao-Yan Wu; Ya-Qing Shen; Yi-Ning Qiu; Run-Ming Jin
Journal:  Curr Med Sci       Date:  2022-03-08

5.  Monocytic myeloid-derived suppressive cells mitigate over-adipogenesis of bone marrow microenvironment in aplastic anemia by inhibiting CD8+ T cells.

Authors:  Ying Qu; Zhengxu Sun; Yan Yuan; Zifeng Li; Fen Wang; Kunpeng Wu; Huihui Yu; Qiwang Lin; He Fei; Jian Chen; Maoxiang Qian; Yunfeng Cheng; Hua Jiang; Tong Chen
Journal:  Cell Death Dis       Date:  2022-07-18       Impact factor: 9.685

Review 6.  Immune system modulation of kidney regeneration--mechanisms and implications.

Authors:  Hans-Joachim Anders
Journal:  Nat Rev Nephrol       Date:  2014-04-29       Impact factor: 28.314

Review 7.  Bone Marrow Micro-Environment in Normal and Deranged Hematopoiesis: Opportunities for Regenerative Medicine and Therapies.

Authors:  Shawn M Sarkaria; Matthew Decker; Lei Ding
Journal:  Bioessays       Date:  2018-01-31       Impact factor: 4.345

8.  Somatic HLA Mutations Expose the Role of Class I-Mediated Autoimmunity in Aplastic Anemia and its Clonal Complications.

Authors:  Daria V Babushok; Jamie L Duke; Hongbo M Xie; Natasha Stanley; Jamie Atienza; Nieves Perdigones; Peter Nicholas; Deborah Ferriola; Yimei Li; Hugh Huang; Wenda Ye; Jennifer J D Morrissette; Jane Kearns; David L Porter; Gregory M Podsakoff; Laurence C Eisenlohr; Jaclyn A Biegel; Stella T Chou; Dimitrios S Monos; Monica Bessler; Timothy S Olson
Journal:  Blood Adv       Date:  2017-10-10

9.  Correlation analysis of severe aplastic anemia immunosuppressive therapy and human leukocyte antigen alleles in pediatric patients.

Authors:  Ru-Ting Fu; Hong-Man Xue; Bi-Hong Zhang; Jian Wang; Shao-Fen Lin; Chun Chen
Journal:  Exp Ther Med       Date:  2015-10-15       Impact factor: 2.447

Review 10.  Special issues related to the diagnosis and management of acquired aplastic anemia in countries with restricted resources, a report on behalf of the Eastern Mediterranean blood and marrow transplantation (EMBMT) group and severe aplastic anemia working party of the European Society for blood and marrow transplantation (SAAWP of EBMT).

Authors:  Raheel Iftikhar; Parvez Ahmad; Regis de Latour; Carlo Dufour; Antonio Risitano; Naeem Chaudhri; Ali Bazarbachi; Josu De La Fuente; Britta Höchsmann; Syed Osman Ahmed; Usama Gergis; Alaa Elhaddad; Constantijn Halkes; Bassim Albeirouti; Sultan Alotaibi; Austin Kulasekararaj; Hazzaa Alzahrani; Tarek Ben Othman; Simone Cesaro; Ali Alahmari; Rawad Rihani; Salem Alshemmari; Amir Ali Hamidieh; Mohamed-Amine Bekadja; Jakob Passweg; Murtadha Al-Khabori; Walid Rasheed; Andrea Bacigalupo; Qamar-Un-Nisa Chaudhry; Per Ljungman; Judith Marsh; Riad El Fakih; Mahmoud Aljurf
Journal:  Bone Marrow Transplant       Date:  2021-05-19       Impact factor: 5.483
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