Literature DB >> 2442414

Action of 3-methylquercetin on poliovirus RNA replication.

J L Castrillo, L Carrasco.   

Abstract

3-Methylquercetin is a natural flavone that powerfully blocks poliovirus replication. This compound inhibits selectively poliovirus RNA synthesis both in infected cells and in cell-free systems. Poliovirus double-stranded RNA (replicative forms) is still made in the presence of this inhibitor, whereas the synthesis of single-stranded RNA and the formation of replicative intermediates are drastically blocked.

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Year:  1987        PMID： 2442414      PMCID： PMC255917     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  22 in total

1.  Poliovirus-induced RNA polymerase and the effects of virus-specific inhibitors on its production.

Authors:  D BALTIMORE; H J EGGERS; R M FRANKLIN; I TAMM
Journal:  Proc Natl Acad Sci U S A       Date:  1963-06       Impact factor: 11.205

2.  Covalent linkage of a protein to a defined nucleotide sequence at the 5'-terminus of virion and replicative intermediate RNAs of poliovirus.

Authors:  J B Flanegan; R F Petterson; V Ambros; N J Hewlett; D Baltimore
Journal:  Proc Natl Acad Sci U S A       Date:  1977-03       Impact factor: 11.205

3.  Initiation of poliovirus plus-strand RNA synthesis in a membrane complex of infected HeLa cells.

Authors:  N Takeda; R J Kuhn; C F Yang; T Takegami; E Wimmer
Journal:  J Virol       Date:  1986-10       Impact factor: 5.103

4.  Characterization of poliovirus-specific structures associated with cytoplasmic membranes.

Authors:  L A Caliguiri; I Tamm
Journal:  Virology       Date:  1970-09       Impact factor: 3.616

5.  Structure of the poliovirus replicative intermediate RNA.

Authors:  D Baltimore
Journal:  J Mol Biol       Date:  1968-03-14       Impact factor: 5.469

6.  Primary structure, gene organization and polypeptide expression of poliovirus RNA.

Authors:  N Kitamura; B L Semler; P G Rothberg; G R Larsen; C J Adler; A J Dorner; E A Emini; R Hanecak; J J Lee; S van der Werf; C W Anderson; E Wimmer
Journal:  Nature       Date:  1981-06-18       Impact factor: 49.962

7.  Dependence of the activity of the poliovirus replicase on the host cell protein.

Authors:  A Dasgupta; P Zabel; D Baltimore
Journal:  Cell       Date:  1980-02       Impact factor: 41.582

8.  3-Methylquercetin is a potent and selective inhibitor of poliovirus RNA synthesis.

Authors:  J L Castrillo; D Vanden Berghe; L Carrasco
Journal:  Virology       Date:  1986-07-15       Impact factor: 3.616

9.  Polyadenylic acid at the 3'-terminus of poliovirus RNA.

Authors:  Y Yogo; E Wimmer
Journal:  Proc Natl Acad Sci U S A       Date:  1972-07       Impact factor: 11.205

10.  A protein covalently linked to poliovirus genome RNA.

Authors:  Y F Lee; A Nomoto; B M Detjen; E Wimmer
Journal:  Proc Natl Acad Sci U S A       Date:  1977-01       Impact factor: 11.205
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  9 in total

1.  Gliotoxin: inhibitor of poliovirus RNA synthesis that blocks the viral RNA polymerase 3Dpol.

Authors:  P L Rodriguez; L Carrasco
Journal:  J Virol       Date:  1992-04       Impact factor: 5.103

2.  Proteolysis of human eukaryotic translation initiation factor eIF4GII, but not eIF4GI, coincides with the shutoff of host protein synthesis after poliovirus infection.

Authors:  A Gradi; Y V Svitkin; H Imataka; N Sonenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1998-09-15       Impact factor: 11.205

3.  Poliovirus infection and expression of the poliovirus protein 2B provoke the disassembly of the Golgi complex, the organelle target for the antipoliovirus drug Ro-090179.

Authors:  I V Sandoval; L Carrasco
Journal:  J Virol       Date:  1997-06       Impact factor: 5.103

4.  Partial purification, kinetic analysis, and amino acid sequence information of a flavonol 3-O-methyltransferase from Serratula tinctoria.

Authors:  Tyng-Shyan Huang; Dominique Anzellotti; Fabienne Dedaldechamp; Ragai K Ibrahim
Journal:  Plant Physiol       Date:  2004-04       Impact factor: 8.340

5.  Quercetin inhibits rhinovirus replication in vitro and in vivo.

Authors:  Shyamala Ganesan; Andrea N Faris; Adam T Comstock; Qiong Wang; Suparna Nanua; Marc B Hershenson; Uma S Sajjan
Journal:  Antiviral Res       Date:  2012-03-23       Impact factor: 5.970

6.  Repurposing potential of Ayurvedic medicinal plants derived active principles against SARS-CoV-2 associated target proteins revealed by molecular docking, molecular dynamics and MM-PBSA studies.

Authors:  Akalesh Kumar Verma; Vikas Kumar; Sweta Singh; Bhabesh Ch Goswami; Ihosvany Camps; Aishwarya Sekar; Sanghwa Yoon; Keun Woo Lee
Journal:  Biomed Pharmacother       Date:  2021-02-03       Impact factor: 7.419

Review 7.  The Role of Micronutrients to Support Immunity for COVID-19 Prevention.

Authors:  Mukhtar H Ahmed; Arez Hassan; Judit Molnár
Journal:  Rev Bras Farmacogn       Date:  2021-09-02       Impact factor: 2.010

8.  Simultaneous determination of esculetin, quercetin-3-O-β-D-glucuronide, quercetin-3-O-β -D-glucuronopyranside methyl ester and quercetin in effective part of Polygonum Perfoliatum L. using high performace liquid chromatography.

Authors:  Dongsheng Fan; Yang Zhao; Xin Zhou; Xiaojian Gong; Chao Zhao
Journal:  Pharmacogn Mag       Date:  2014-07       Impact factor: 1.085

Review 9.  Picornavirus inhibitors.

Authors:  L Carrasco
Journal:  Pharmacol Ther       Date:  1994       Impact factor: 12.310
  9 in total

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