| Literature DB >> 24422592 |
Gang Ding1, Hailou Wang, Li Li, Bo Song, Hong Chen, Hongwu Zhang, Xinzhong Liu, Zhongmei Zou.
Abstract
Trichodermone (1), the first spiro-cytochalasan with an unprecedented tetracyclic nucleus (7/5/6/5), together with its possible biosynthetic precursor aspochalasin D (2), was isolated from the endophytic fungus Trichoderma gamsii. Compound 2 displayed moderate inhibitory activity against HeLa cells with an IC50 value of 5.72 μM.Entities:
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Year: 2014 PMID: 24422592 DOI: 10.1021/np4007487
Source DB: PubMed Journal: J Nat Prod ISSN: 0163-3864 Impact factor: 4.050