Literature DB >> 24421467

Teriflunomide.

Dennis J Cada1, Kendra Demaris2, Terri L Levien3, Danial E Baker4.   

Abstract

Each month, subscribers to The Formulary Monograph Service receive 5 to 6 well-documented monographs on drugs that are newly released or are in late phase 3 trials. The monographs are targeted to Pharmacy & Therapeutics Committees. Subscribers also receive monthly 1-page summary monographs on agents that are useful for agendas and pharmacy/nursing in-services. A comprehensive target drug utilization evaluation/medication use evaluation (DUE/MUE) is also provided each month. With a subscription, the monographs are sent in print and are also available on-line. Monographs can be customized to meet the needs of a facility. Subscribers to The Formulary Monograph Service also receive access to a pharmacy bulletin board, The Formulary Information Exchange (The F.I.X.). All topics pertinent to clinical and hospital pharmacy are discussed on The F.I.X. A drug class review is now published monthly with The Formulary Monograph Service. Through the cooperation of The Formulary, Hospital Pharmacy publishes selected reviews in this column. For more information about The Formulary Monograph Service or The F.I.X., call The Formulary at 800-322-4349. The March 2013 monograph topics are apixaban, bedaquiline, raxibacumab, teduglutide, and loxapine inhalation. The DUE/MUE is on apixaban.

Entities:  

Year:  2013        PMID: 24421467      PMCID: PMC3839508          DOI: 10.1310/hpj4803-231

Source DB:  PubMed          Journal:  Hosp Pharm        ISSN: 0018-5787


  15 in total

1.  A771726, the active metabolite of leflunomide, directly inhibits the activity of cyclo-oxygenase-2 in vitro and in vivo in a substrate-sensitive manner.

Authors:  L C Hamilton; I Vojnovic; T D Warner
Journal:  Br J Pharmacol       Date:  1999-08       Impact factor: 8.739

2.  The immunosuppressive metabolite of leflunomide, A77 1726, affects murine T cells through two biochemical mechanisms.

Authors:  R T Elder; X Xu; J W Williams; H Gong; A Finnegan; A S Chong
Journal:  J Immunol       Date:  1997-07-01       Impact factor: 5.422

Review 3.  Immune mechanisms of new therapeutic strategies in MS: teriflunomide.

Authors:  Malte C Claussen; Thomas Korn
Journal:  Clin Immunol       Date:  2011-03-01       Impact factor: 3.969

Review 4.  Pathophysiology of multiple sclerosis and the place of teriflunomide.

Authors:  R Gold; J S Wolinsky
Journal:  Acta Neurol Scand       Date:  2010-09-29       Impact factor: 3.209

5.  Leflunomide suppresses TNF-induced cellular responses: effects on NF-kappa B, activator protein-1, c-Jun N-terminal protein kinase, and apoptosis.

Authors:  S K Manna; A Mukhopadhyay; B B Aggarwal
Journal:  J Immunol       Date:  2000-11-15       Impact factor: 5.422

6.  Randomized trial of oral teriflunomide for relapsing multiple sclerosis.

Authors:  Paul O'Connor; Jerry S Wolinsky; Christian Confavreux; Giancarlo Comi; Ludwig Kappos; Tomas P Olsson; Hadj Benzerdjeb; Philippe Truffinet; Lin Wang; Aaron Miller; Mark S Freedman
Journal:  N Engl J Med       Date:  2011-10-06       Impact factor: 91.245

7.  Modulation of effector cell functions in experimental autoimmune encephalomyelitis by leflunomide--mechanisms independent of pyrimidine depletion.

Authors:  Thomas Korn; Tim Magnus; Klaus Toyka; Stefan Jung
Journal:  J Leukoc Biol       Date:  2004-08-24       Impact factor: 4.962

8.  Inhibition of the epidermal growth factor receptor tyrosine kinase activity by leflunomide.

Authors:  T Mattar; K Kochhar; R Bartlett; E G Bremer; A Finnegan
Journal:  FEBS Lett       Date:  1993-11-15       Impact factor: 4.124

9.  Long-term follow-up of a phase 2 study of oral teriflunomide in relapsing multiple sclerosis: safety and efficacy results up to 8.5 years.

Authors:  Christian Confavreux; David K Li; Mark S Freedman; Philippe Truffinet; Hadj Benzerdjeb; Dazhe Wang; Amit Bar-Or; Anthony L Traboulsee; Lucy E Reiman; Paul W O'Connor
Journal:  Mult Scler       Date:  2012-02-03       Impact factor: 6.312

10.  Review of teriflunomide and its potential in the treatment of multiple sclerosis.

Authors:  Clemens Warnke; Gerd Meyer zu Hörste; Hans-Peter Hartung; Olaf Stüve; Bernd C Kieseier
Journal:  Neuropsychiatr Dis Treat       Date:  2009-06-10       Impact factor: 2.570

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  3 in total

Review 1.  Multiple Sclerosis: Therapeutic Strategies on the Horizon.

Authors:  Ramya Talanki Manjunatha; Salma Habib; Sai Lahari Sangaraju; Daniela Yepez; Xavier A Grandes
Journal:  Cureus       Date:  2022-05-10

2.  Pregnancy Outcomes in Men and Women Treated With Teriflunomide. A Population-Based Nationwide Danish Register Study.

Authors:  Johanna Balslev Andersen; Julie Yoon Moberg; Tim Spelman; Melinda Magyari
Journal:  Front Immunol       Date:  2018-11-23       Impact factor: 7.561

3.  The Selective Oral Immunomodulator Vidofludimus in Patients with Active Rheumatoid Arthritis: Safety Results from the COMPONENT Study.

Authors:  Andreas Muehler; Hella Kohlhof; Manfred Groeppel; Daniel Vitt
Journal:  Drugs R D       Date:  2019-12
  3 in total

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