| Literature DB >> 24421280 |
Anthony P Raphael1, Clare A Primiero, Lynlee L Lin, Ross Flewell Smith, Philip Dyer, H Peter Soyer, Tarl W Prow.
Abstract
Delivery of therapeutics into skin is hindered by the epidermal barriers. To overcome these barriers for the treatment of skin diseases, a cutaneous delivery method capable of field treatment using silica-elongated microparticles is developed. The microparticles are massaged into the skin using a 3D-printed microtextured applicator resulting in significant field-directed drug delivery enhancement.Entities:
Keywords: drug delivery; microneedles; microparticles; silica; skin
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Year: 2014 PMID： 24421280 DOI： 10.1002/adhm.201300517
Source DB: PubMed Journal: Adv Healthc Mater ISSN： 2192-2640 Impact factor: 9.933