Literature DB >> 24421252

Isolated limb perfusion with melphalan for melanoma.

Omgo E Nieweg1, Bin B R Kroon.   

Abstract

Isolated limb perfusion with melphalan is a well-established and effective treatment for inoperable melanoma metastases of the extremities, with an overall response rate of 80% and a complete response rate of 54%. The surgical technique is complex and serious morbidity can occur, but with attention to detail major side effects can be kept to a minimum. This article reviews the technique, results and other aspects of this sophisticated form of treatment.
© 2014 Wiley Periodicals, Inc.

Entities:  

Keywords:  limb perfusion; metastases; regional chemotherapy; review

Mesh：

Substances：

Year:  2014        PMID： 24421252     DOI： 10.1002/jso.23558

Source DB:  PubMed          Journal:  J Surg Oncol        ISSN： 0022-4790            Impact factor:   3.454


  9 in total

1.  Intravitreous Cutaneous Metastatic Melanoma in the Era of Checkpoint Inhibition: Unmasking and Masquerading.

Authors:  Jasmine H Francis; Duncan Berry; David H Abramson; Christopher A Barker; Chris Bergstrom; Hakan Demirci; Michael Engelbert; Hans Grossniklaus; Baker Hubbard; Codrin E Iacob; Korey Jaben; Madhavi Kurli; Michael A Postow; Jedd D Wolchok; Ivana K Kim; Jill R Wells
Journal:  Ophthalmology       Date:  2019-09-24       Impact factor: 12.079

2.  A murine model of targeted infusion for intracranial tumors.

Authors:  Minhyung Kim; Tara A Barone; Natalia Fedtsova; Anatoli Gleiberman; Chandler D Wilfong; Julie A Alosi; Robert J Plunkett; Andrei Gudkov; Joseph J Skitzki
Journal:  J Neurooncol       Date:  2015-09-16       Impact factor: 4.130

Review 3.  The Current State of Treatment and Future Directions in Cutaneous Malignant Melanoma.

Authors:  Madison Ernst; Alessio Giubellino
Journal:  Biomedicines       Date:  2022-03-31

4.  Chemoreduction of Orbital Recurrence of Uveal Melanoma by Intra-Arterial Melphalan.

Authors:  Jasmine H Francis; Christopher A Barker; Vivian T Yin; Richard D Carvajal; Paul Chapman; David H Abramson; Y Pierre Gobin
Journal:  Ocul Oncol Pathol       Date:  2018-10-09

5.  Dipeptidyl peptidase IV as a potential target for selective prodrug activation and chemotherapeutic action in cancers.

Authors:  Arik Dahan; Omri Wolk; Peihua Yang; Sachin Mittal; Zhiqian Wu; Christopher P Landowski; Gordon L Amidon
Journal:  Mol Pharm       Date:  2014-11-13       Impact factor: 4.939

6.  Clinical characteristics of critically ill cancer patients who are undergoing isolated limb perfusion.

Authors:  Silvio A Ñamendys-Silva; Arturo M Ruiz-Beltran; Mireya Barragán-Dessavre; Andoreni R Bautista-Ocampo; Abelardo Meneses-García; Octavio González-Chon; Angel Herrera-Gómez
Journal:  Mol Clin Oncol       Date:  2017-08-31

7.  Combination intravitreous melphalan and bevacizumb for cutaneous metastatic melanoma to the vitreous and retina.

Authors:  Jasmine H Francis; Julia Canestraro; David H Abramson; Christopher A Barker; Alexander N Shoushtari
Journal:  Am J Ophthalmol Case Rep       Date:  2022-04-09

8.  In vivo reflectance confocal microscopy: a useful non-invasive tool to assess the response to isolated limb perfusion for superficial pigmented melanoma in-transit metastatic disease. Report of a case.

Authors:  Rastine Merat; Wolf-Henning Boehncke; Gürkan Kaya
Journal:  Dermatol Pract Concept       Date:  2017-04-30

9.  Comparison of Survival in Patients with Isolated Peritoneal Carcinomatosis from Colorectal Cancer Treated with Cytoreduction and Melphalan or Mitomycin-C as Hyperthermic Intraperitoneal Chemotherapy Agent.

Authors:  Arkadii Sipok; Armando Sardi; Carol Nieroda; Mary Caitlin King; Michelle Sittig; Vadim Gushchin
Journal:  Int J Surg Oncol       Date:  2018-12-13
  9 in total

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