Literature DB >> 24420749

Molecular aspects of cholangiocarcinoma.

Kaoru Kiguchi1.   

Abstract

Novel targets for therapeutic or chemopreventive approaches against cholangiocarcinoma (CCA) are urgently needed. In this review article, we discuss the molecular aspects of CCA including the role of erbB receptor tyrosine kinases (RTKs), downstream signaling pathways of these erbB RTKs, inflammatory mediators during gallbladder carcinogenesis and bile acids based on our study using a mouse model for human CCA (BK5.erbB2 mice) as well as additional information in the literature.
© 2014 Japanese Society of Hepato-Biliary-Pancreatic Surgery.

Entities:  

Keywords:  COX-2 and bile acid; Cholangiocarcinoma; Epidermal growth factor receptor · erbB2

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Year:  2014        PMID： 24420749     DOI： 10.1002/jhbp.66

Source DB:  PubMed          Journal:  J Hepatobiliary Pancreat Sci        ISSN： 1868-6974            Impact factor:   7.027


  2 in total

1.  Taurocholate Induces Cyclooxygenase-2 Expression via the Sphingosine 1-phosphate Receptor 2 in a Human Cholangiocarcinoma Cell Line.

Authors:  Runping Liu; Xiaojiaoyang Li; Xiaoyan Qiang; Lan Luo; Phillip B Hylemon; Zhenzhou Jiang; Luyong Zhang; Huiping Zhou
Journal:  J Biol Chem       Date:  2015-10-30       Impact factor: 5.157

Review 2.  Endoscopic Applications of Near-Infrared Photoimmunotherapy (NIR-PIT) in Cancers of the Digestive and Respiratory Tracts.

Authors:  Hideyuki Furumoto; Takuya Kato; Hiroaki Wakiyama; Aki Furusawa; Peter L Choyke; Hisataka Kobayashi
Journal:  Biomedicines       Date:  2022-04-04
  2 in total

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