Sumiko Kurioka1, Seichi Horie, Akiomi Inoue, Kosuke Mafune, Yuki Tsuda, Yutaka Otsuji. 1. aDepartment of Health Policy and Management, Institute of Industrial Ecological Sciences bDepartment of Mental Health, Institute of Industrial Ecological Sciences cThe Second Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Abstract
OBJECTIVE: Prehypertension is a known risk factor for hypertension in individuals aged less than 20 or more than 35 years, but no large studies have investigated this risk in individuals aged 20-34 years. This study investigated progression to hypertension in nonhypertensive individuals aged 20-34 years and compared this group with individuals aged 35-64 years. METHODS: A total of 12,639 nonhypertensive individuals aged 20-64 years were followed from 1999 to 2008. Hazard ratios for progression to hypertension were calculated for men and women according to three blood pressure (BP) categories (optimal BP: <120/80 mmHg; normal BP: 120-129/80-84 mmHg; high-normal BP: 130-139/85-89 mmHg) and three age groups (20-34, 35-49 and 50-64 years). RESULTS: Progression to hypertension occurred in 4617 individuals (36.5%). The risk of progression to hypertension increased significantly with increasing baseline BP category in men and women in all age groups. The association between baseline BP and progression to hypertension was stronger in the group aged 20-34 years than in the older age groups, especially in men. CONCLUSION: The results of this study confirm that normal or high-normal BP increases the risk of progression to hypertension in individuals aged 20-34 years. In men, the association between baseline BP and progression to hypertension is stronger in this age group than in older age groups. Health providers should be aware that normal or high-normal BP is a risk factor for progression to hypertension even in individuals aged 20-34 years.
OBJECTIVE:Prehypertension is a known risk factor for hypertension in individuals aged less than 20 or more than 35 years, but no large studies have investigated this risk in individuals aged 20-34 years. This study investigated progression to hypertension in nonhypertensive individuals aged 20-34 years and compared this group with individuals aged 35-64 years. METHODS: A total of 12,639 nonhypertensive individuals aged 20-64 years were followed from 1999 to 2008. Hazard ratios for progression to hypertension were calculated for men and women according to three blood pressure (BP) categories (optimal BP: <120/80 mmHg; normal BP: 120-129/80-84 mmHg; high-normal BP: 130-139/85-89 mmHg) and three age groups (20-34, 35-49 and 50-64 years). RESULTS: Progression to hypertension occurred in 4617 individuals (36.5%). The risk of progression to hypertension increased significantly with increasing baseline BP category in men and women in all age groups. The association between baseline BP and progression to hypertension was stronger in the group aged 20-34 years than in the older age groups, especially in men. CONCLUSION: The results of this study confirm that normal or high-normal BP increases the risk of progression to hypertension in individuals aged 20-34 years. In men, the association between baseline BP and progression to hypertension is stronger in this age group than in older age groups. Health providers should be aware that normal or high-normal BP is a risk factor for progression to hypertension even in individuals aged 20-34 years.
Authors: Shakia T Hardy; Katelyn M Holliday; Sujatro Chakladar; Joseph C Engeda; Norrina B Allen; Gerardo Heiss; Donald M Lloyd-Jones; Pamela J Schreiner; Christina M Shay; Danyu Lin; Donglin Zeng; Christy L Avery Journal: JAMA Cardiol Date: 2017-06-01 Impact factor: 30.154
Authors: Sandra Costa Fuchs; Carlos E Poli-de-Figueiredo; José A Figueiredo Neto; Luiz César N Scala; Paul K Whelton; Francisca Mosele; Renato Bandeira de Mello; José F Vilela-Martin; Leila B Moreira; Hilton Chaves; Marco Mota Gomes; Marcos R de Sousa; Ricardo Pereira E Silva; Iran Castro; Evandro José Cesarino; Paulo Cesar Jardim; João Guilherme Alves; André Avelino Steffens; Andréa Araujo Brandão; Fernanda M Consolim-Colombo; Paulo Ricardo de Alencastro; Abrahão Afiune Neto; Antônio C Nóbrega; Roberto Silva Franco; Dario C Sobral Filho; Alexandro Bordignon; Fernando Nobre; Rosane Schlatter; Miguel Gus; Felipe C Fuchs; Otávio Berwanger; Flávio D Fuchs Journal: J Am Heart Assoc Date: 2016-12-13 Impact factor: 5.501