Literature DB >> 24419076

Basis of Treg development in the thymus.

Xuguang Tai1, Alfred Singer1.   

Abstract

Entities:  

Keywords:  Foxp3; IL-2; apoptosis; clonal deletion; costimulation; regulatory T-cells; tolerance; γc cytokines

Mesh：

Substances：

Year:  2014        PMID： 24419076      PMCID： PMC6690604          DOI： 10.4161/cc.27787

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


× No keyword cloud information.
  8 in total

1.  CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2.

Authors:  Xuguang Tai; Michelle Cowan; Lionel Feigenbaum; Alfred Singer
Journal:  Nat Immunol       Date:  2005-01-09       Impact factor: 25.606

Review 2.  Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice.

Authors:  Alfred Singer; Stanley Adoro; Jung-Hyun Park
Journal:  Nat Rev Immunol       Date:  2008-10       Impact factor: 53.106

3.  Foxp3 transcription factor is proapoptotic and lethal to developing regulatory T cells unless counterbalanced by cytokine survival signals.

Authors:  Xuguang Tai; Batu Erman; Amala Alag; Jie Mu; Motoko Kimura; Gil Katz; Terry Guinter; Tom McCaughtry; Ruth Etzensperger; Lionel Feigenbaum; Dinah S Singer; Alfred Singer
Journal:  Immunity       Date:  2013-06-06       Impact factor: 31.745

Review 4.  Regulatory T cells: mechanisms of differentiation and function.

Authors:  Steven Z Josefowicz; Li-Fan Lu; Alexander Y Rudensky
Journal:  Annu Rev Immunol       Date:  2012-01-06       Impact factor: 28.527

5.  Foxp3 occupancy and regulation of key target genes during T-cell stimulation.

Authors:  Alexander Marson; Karsten Kretschmer; Garrett M Frampton; Elizabeth S Jacobsen; Julia K Polansky; Kenzie D MacIsaac; Stuart S Levine; Ernest Fraenkel; Harald von Boehmer; Richard A Young
Journal:  Nature       Date:  2007-01-21       Impact factor: 49.962

6.  Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire.

Authors:  Matthew A Burchill; Jianying Yang; Kieng B Vang; James J Moon; H Hamlet Chu; Chan-Wang J Lio; Amanda L Vegoe; Chyi-Song Hsieh; Marc K Jenkins; Michael A Farrar
Journal:  Immunity       Date:  2008-01       Impact factor: 31.745

7.  A two-step process for thymic regulatory T cell development.

Authors:  Chan-Wang Joaquim Lio; Chyi-Song Hsieh
Journal:  Immunity       Date:  2008-01       Impact factor: 31.745

8.  Clonal deletion and the fate of autoreactive thymocytes that survive negative selection.

Authors:  Leonid A Pobezinsky; Georgi S Angelov; Xuguang Tai; Susanna Jeurling; François Van Laethem; Lionel Feigenbaum; Jung-Hyun Park; Alfred Singer
Journal:  Nat Immunol       Date:  2012-04-29       Impact factor: 25.606
  8 in total
  5 in total

Review 1.  CD28-CD80/86 and CD40-CD40L Interactions Promote Thymic Tolerance by Regulating Medullary Epithelial Cell and Thymocyte Development.

Authors:  Joy A Williams; Xuguang Tai; Richard J Hodes
Journal:  Crit Rev Immunol       Date:  2015       Impact factor: 2.214

2.  Generation of Foxp3+CD25- Regulatory T-Cell Precursors Requires c-Rel and IκBNS.

Authors:  Marc Schuster; Carlos Plaza-Sirvent; Alexander Visekruna; Jochen Huehn; Ingo Schmitz
Journal:  Front Immunol       Date:  2019-07-10       Impact factor: 7.561

3.  The small intestine epithelium exempts Foxp3+ Tregs from their IL-2 requirement for homeostasis and effector function.

Authors:  Praveen Prakhar; Jaylene Alvarez-DelValle; Hilary Keller; Assiatu Crossman; Xuguang Tai; Yoo Kyoung Park; Jung-Hyun Park
Journal:  JCI Insight       Date:  2021-11-08

Review 4.  Role of Cytokines in Thymic Regulatory T Cell Generation: Overview and Updates.

Authors:  Mei Tang; Fuya Jia; Fang Nan; Fengqiong Zuo; Zhu Yuan; Dunfang Zhang
Journal:  Front Immunol       Date:  2022-03-31       Impact factor: 7.561

5.  Phosphate Transporter Profiles in Murine and Human Thymi Identify Thymocytes at Distinct Stages of Differentiation.

Authors:  Alice Machado; Marie Pouzolles; Sarah Gailhac; Vanessa Fritz; Marco Craveiro; Uriel López-Sánchez; Taisuke Kondo; Francesca Pala; Marita Bosticardo; Luigi D Notarangelo; Vincent Petit; Naomi Taylor; Valérie S Zimmermann
Journal:  Front Immunol       Date:  2020-07-22       Impact factor: 7.561
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.