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Literature DB >> 24418656

Chaetoglobosin Y, a new cytochalasan from Chaetomium globosum.

Qi-Chang Zheng¹, Ming-Zhu Kong², Qin Zhao¹, Guo-Dong Chen³, Hai-Yan Tian¹, Xiao-Xia Li¹, Liang-Dong Guo⁴, Jia Li⁵, Yi-Zhi Zheng², Hao Gao⁶.

Abstract

Chaetoglobosin Y (1), was isolated from the endolichenic fungal strain Chaetomium globosum (No. 64-5-8-2), along with related six known cytochalasans, chaetoglobosin Fex (2), chaetoglobosin E (3), isochaetoglobosin D (4), chaetoglobosin G (5), cytoglobosin B (6), and cytoglobosin C (7). Their structures were determined by detailed spectroscopic analyses and comparison with those of the closely related compounds previously reported. The cytotoxicity to HCT-116 cell line of 2-7 was evaluated in vitro with doxorubicin as positive control.

Entities: Chemical Disease Species

Keywords: Chaetoglobosins; Chaetomiaceae; Chaetomium globosum; Cytochalasans; Cytotoxicity

Mesh：

Substances：

Year: 2014 PMID： 24418656 DOI： 10.1016/j.fitote.2013.12.022

Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882

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Cited

10 in total

1. Progress in the Chemistry of Cytochalasans.

Authors: Hucheng Zhu; Chunmei Chen; Qingyi Tong; Yuan Zhou; Ying Ye; Lianghu Gu; Yonghui Zhang
Journal: Prog Chem Org Nat Prod Date: 2021

2. Cytochalasans from the Endophytic Fungus Phomopsis sp. shj2 and Their Antimigratory Activities.

Authors: Bing-Chao Yan; Wei-Guang Wang; Ling-Mei Kong; Jian-Wei Tang; Xue Du; Yan Li; Pema-Tenzin Puno
Journal: J Fungi (Basel) Date: 2022-05-23

3. Ijuhya vitellina sp. nov., a novel source for chaetoglobosin A, is a destructive parasite of the cereal cyst nematode Heterodera filipjevi.

Authors: Samad Ashrafi; Soleiman Helaly; Hans-Josef Schroers; Marc Stadler; Katja R Richert-Poeggeler; Abdelfattah A Dababat; Wolfgang Maier
Journal: PLoS One Date: 2017-07-12 Impact factor: 3.240

4. Biological Evaluation of Endophytic Fungus Chaetomium sp. NF15 of Justicia adhatoda L.: A Potential Candidate for Drug Discovery.

Authors: Nighat Fatima; Usman Mukhtar; Muneer Ahmed Qazi; Muniba Jadoon; Safia Ahmed
Journal: Jundishapur J Microbiol Date: 2016-06-05 Impact factor: 0.747

Chaetoglobosin Y, a new cytochalasan from Chaetomium globosum.

1. Progress in the Chemistry of Cytochalasans.

2. Cytochalasans from the Endophytic Fungus Phomopsis sp. shj2 and Their Antimigratory Activities.

3. Ijuhya vitellina sp. nov., a novel source for chaetoglobosin A, is a destructive parasite of the cereal cyst nematode Heterodera filipjevi.

4. Biological Evaluation of Endophytic Fungus Chaetomium sp. NF15 of Justicia adhatoda L.: A Potential Candidate for Drug Discovery.

5. Effect of Usnic Acid on Osteoclastogenic Activity.

6. Diagnostically analyzing ¹H NMR spectra of sub-types in chaetoglobosins for dereplication.

7. Nine new cytochalasan alkaloids from Chaetomium globosum TW1-1 (Ascomycota, Sordariales).

8. Bioactive Chaetoglobosins from the Mangrove Endophytic Fungus Penicillium chrysogenum.

9. Chaetomadrasins A and B, Two New Cytotoxic Cytochalasans from Desert Soil-Derived Fungus Chaetomium madrasense 375.

10. HPLC-DAD-Guided Isolation of Diversified Chaetoglobosins from the Coral-Associated Fungus Chaetomium globosum C2F17.