| Literature DB >> 24417759 |
Maiken Cavling Arendrup1, Manuel Cuenca-Estrella, Cornelia Lass-Flörl, William W Hope.
Abstract
The European Committee on Antimicrobial Susceptibility Testing Subcommittee on Antifungal Susceptibility Testing has determined breakpoints for micafungin and revised breakpoints for anidulafungin and fluconazole for Candida spp. This Technical Note is based on the corresponding rationale documents (http://www.eucast.org). The micafungin breakpoints are based on PK data, animal PK/PD data, microbiological data and clinical experience. The anidulafungin breakpoints for C. parapsilosis and fluconazole breakpoints for C. glabrata have been modified to species-specific values that categorise the wild-type as intermediate to accommodate use of these compounds in some clinical situations.Entities:
Keywords: Candida; EUCAST breakpoints; MIC; microdilution; susceptibility testing
Mesh:
Substances:
Year: 2014 PMID: 24417759 DOI: 10.1111/myc.12170
Source DB: PubMed Journal: Mycoses ISSN: 0933-7407 Impact factor: 4.377