Andrea Streng1, Johannes G Liese2. 1. Department of Paediatrics, University of Würzburg, Josef-Schneider-Str. 2, 97080 Würzburg, Germany. Electronic address: Streng_A@ukw.de. 2. Department of Paediatrics, University of Würzburg, Josef-Schneider-Str. 2, 97080 Würzburg, Germany.
Abstract
BACKGROUND: Germany introduced routine varicella (V) vaccination in 2004. Due to a slightly increased risk of febrile convulsions after first-dose application of combined measles-mumps-rubella-varicella (MMRV) vaccine separate first-dose vaccinations with MMR and monovalent V vaccine were recommended in September 2011. METHODS: We compared V and MMR vaccinations in paediatric practices from two surveillance regions (Munich and Würzburg) one year before and after the change in the recommendation. RESULTS: A total of 1405/326 monthly reports were provided by a monthly average of 79/14 practices participating in Munich/Würzburg. V first-dose vaccinations (monovalent V or MMRV vaccine) declined by 12% in Munich (from 10.1 to 8.9 vaccinations per month and practice; p<0.005) and by 4% in Würzburg (from 9.9 to 9.5; p=0.620), respectively. First-dose vaccinations for MMR (MMR or MMRV vaccine) did not change significantly in both regions. CONCLUSION: Acceptance of V vaccination depends in part on the use of combination vaccine.
BACKGROUND: Germany introduced routine varicella (V) vaccination in 2004. Due to a slightly increased risk of febrile convulsions after first-dose application of combined measles-mumps-rubella-varicella (MMRV) vaccine separate first-dose vaccinations with MMR and monovalent V vaccine were recommended in September 2011. METHODS: We compared V and MMR vaccinations in paediatric practices from two surveillance regions (Munich and Würzburg) one year before and after the change in the recommendation. RESULTS: A total of 1405/326 monthly reports were provided by a monthly average of 79/14 practices participating in Munich/Würzburg. V first-dose vaccinations (monovalent V or MMRV vaccine) declined by 12% in Munich (from 10.1 to 8.9 vaccinations per month and practice; p<0.005) and by 4% in Würzburg (from 9.9 to 9.5; p=0.620), respectively. First-dose vaccinations for MMR (MMR or MMRV vaccine) did not change significantly in both regions. CONCLUSION: Acceptance of V vaccination depends in part on the use of combination vaccine.
Authors: Kristine Macartney; Heather F Gidding; Lieu Trinh; Han Wang; Aditi Dey; Brynley Hull; Karen Orr; Jocelynne McRae; Peter Richmond; Michael Gold; Nigel Crawford; Jennifer A Kynaston; Peter McIntyre; Nicholas Wood Journal: JAMA Pediatr Date: 2017-10-01 Impact factor: 16.193
Authors: Katsiaryna Holl; Christophe Sauboin; Emanuele Amodio; Paolo Bonanni; Giovanni Gabutti Journal: BMC Public Health Date: 2016-10-21 Impact factor: 3.295