Literature DB >> 24411661

Alcohol and substance use in multiple sclerosis.

Meghan Beier1, Vanessa D'Orio2, Jessica Spat2, Melissa Shuman2, Frederick W Foley2.   

Abstract

BACKGROUND: Few studies have examined the prevalence of alcohol and drug use in individuals with multiple sclerosis (MS). The current study sought to examine the prevalence and associated demographic, disease-related, and psychological correlates of substance use in an East Coast United States outpatient MS sample.
METHODS: 157 individuals with MS completed questionnaires prior to, during or after their visit with an MS neurologist. These questionnaires included: the Alcohol Use Disorders Identification Test-Consumption (AUDIT-C), CAGE, CAGE-Adapted to Include Drugs (CAGE-AID), Patient Health Questionnaire-9 item (PHQ-9), Beck Depression Inventory-Second Edition (BDI-II) and Hospital Anxiety and Depression Scale-Anxiety (HADS-A).
RESULTS: On the AUDIT-C, 40% of individuals with MS met or exceeded the cutoff for excessive alcohol use. They were more highly educated and younger than non-drinkers. Utilizing the CAGE, 6% of the sample met criteria for a lifetime history of excessive alcohol use and men endorsed higher rates of alcohol use than women. Only a small portion of the sample endorsed a history of drug use (CAGE-AID, 4%). Drug use was associated with greater disability and depression symptoms, but lower self-reported anxiety.
CONCLUSIONS: Current alcohol use was prevalent in this sample, and excessive use was associated with men, younger age, and more education. Reported drug use was minimal and associated with greater disability, more self-reported depression, but fewer anxiety symptoms.
Copyright © 2013 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Alcohol use; Anxiety; Depression; Disability; Drug abuse; Multiple sclerosis

Mesh:

Year:  2013        PMID: 24411661     DOI: 10.1016/j.jns.2013.12.029

Source DB:  PubMed          Journal:  J Neurol Sci        ISSN: 0022-510X            Impact factor:   3.181


  7 in total

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Journal:  J Neurol       Date:  2016-01-02       Impact factor: 4.849

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3.  Individual and Co-occurring SNAP Risk Factors: Smoking, Nutrition, Alcohol Consumption, and Physical Activity in People with Multiple Sclerosis.

Authors:  Julia M Balto; Ipek Ensari; Elizabeth A Hubbard; Naiman Khan; Jennifer L Barnes; Robert W Motl
Journal:  Int J MS Care       Date:  2016 Nov-Dec

4.  Transgenic mice with increased astrocyte expression of CCL2 show altered behavioral effects of alcohol.

Authors:  Jennifer G Bray; Amanda J Roberts; Donna L Gruol
Journal:  Neuroscience       Date:  2017-04-19       Impact factor: 3.590

5.  Risk of Psychiatric Disorders in Multiple Sclerosis: A Nationwide Cohort Study in an Asian Population.

Authors:  Wu-Chien Chien; Ren-Jei Chung; Bing-Long Wang; Nian-Sheng Tzeng; Yao-Ching Huang; Chi-Hsiang Chung; Hsin-An Chang; Yu-Chen Kao; Fang-Jung Wan; Shi-Hao Huang; Richard S Wang; Chien-An Sun
Journal:  Neuropsychiatr Dis Treat       Date:  2021-02-22       Impact factor: 2.570

6.  Adverse health behaviours are associated with depression and anxiety in multiple sclerosis: A prospective multisite study.

Authors:  Kyla A McKay; Helen Tremlett; John D Fisk; Scott B Patten; Kirsten Fiest; Lindsay Berrigan; Ruth Ann Marrie
Journal:  Mult Scler       Date:  2015-08-05       Impact factor: 6.312

7.  Prevalence and Risk Factors of Substance Use Disorder in Rheumatoid Arthritis.

Authors:  Kaarina Kowalec; Heather Carney; Mitulkumar Patel; Carol Hitchon; James M Bolton; Scott B Patten; Lesley A Graff; Charles N Bernstein; Christine Peschken; Ruth Ann Marrie
Journal:  ACR Open Rheumatol       Date:  2021-09-28
  7 in total

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