Literature DB >> 2441004

A highly abundant transcript in adult murine cerebellar granule cells contains repetitive sequences homologous to L1.

H Schaal, D Goldowitz, U A Heinlein, A Unterbeck, C Ruppert, T Papenbrock, B Müller-Hill, W Vielmetter, W Wille.   

Abstract

Cloned cDNA from adult mouse cerebellum composed of subsequences homologous to the L1Md consensus sequence (long interspersed repetitive element "LINE" family of the mouse) hybridizes specifically with large nuclear poly(A)+RNAs that are highly concentrated in the murine and rat cerebellum. These homogeneous L1-related transcripts were localized in the mouse CNS by in situ hybridization with 3H- and biotin-labeled DNA probes. They were found to hybridize to cerebellar granule cells specifically.

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Year:  1987        PMID: 2441004      PMCID: PMC6568952     

Source DB:  PubMed          Journal:  J Neurosci        ISSN: 0270-6474            Impact factor:   6.167


  1 in total

1.  The R-Operon: A Model of Repetitive DNA-Organized Transcriptional Compartmentation of Eukaryotic Chromosomes for Coordinated Gene Expression.

Authors:  Shao-Jun Tang
Journal:  Genes (Basel)       Date:  2016-04-22       Impact factor: 4.096

  1 in total

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