Literature DB >> 24409948

The effect of intravitreal bevacizumab as a pretreatment of vitrectomy for diabetic vitreous hemorrhage on recurrent hemorrhage.

Sule Berk Ergun1, Yasin Toklu, Hasan Basri Cakmak, Sabri Raza, Saban Simsek.   

Abstract

PURPOSE: This study was constructed to compare the rate of rehemorrhage in patients with diabetic vitreous hemorrhage (VH) undergoing pars plana vitrectomy (PPV) with versus without preoperative intravitreal bevacizumab (IVB) injection.
METHODS: It is a retrospective chart review of all patients who had undergone PPV for diabetic VH from January 2008 to January 2011. Patients who had undergone IVB injection before PPV were assigned to Group 1; the others were assigned to Group 2. Postoperative VH was the main outcome.
RESULTS: A total of 65 eyes of 60 patients (19 eyes in Group 1 and 46 eyes in Group 2) were examined. Postoperative VH occured in three eyes (15.8%) in Group 1 and in 13 eyes (28.3%) in Group 2, but this was not statistically significant (p: 0.347).
CONCLUSION: Further studies to evaluate the effect of IVB on postoperative VH are needed.

Entities:  

Keywords:  Bevacizumab; Proliferative diabetic retinopathy; intravitreal injection; vitrectomy; vitreous hemorrhage

Mesh:

Substances:

Year:  2014        PMID: 24409948     DOI: 10.3109/08820538.2013.835847

Source DB:  PubMed          Journal:  Semin Ophthalmol        ISSN: 0882-0538            Impact factor:   1.975


  6 in total

Review 1.  Surgery for Diabetic Eye Complications.

Authors:  María H Berrocal; Luis A Acaba; Alexandra Acaba
Journal:  Curr Diab Rep       Date:  2016-10       Impact factor: 4.810

2.  Neovascular glaucoma after vitrectomy in patients with proliferative diabetic retinopathy.

Authors:  Jin-Woo Kwon; Donghyun Jee; Tae Yoon La
Journal:  Medicine (Baltimore)       Date:  2017-03       Impact factor: 1.889

3.  Outcomes of preoperative bevacizumab in diabetics with nonclearing vitreous hemorrhage without tractional detachment - A quasi-randomized retrospective study.

Authors:  Debdulal Chakraborty; Aniruddha Maiti; Aditya Kelkar; Sabyasachi Sengupta; Sangeeta Roy; Mounika Bolisetty; Akshay Kothari; Jaydeep Majumder
Journal:  Indian J Ophthalmol       Date:  2021-11       Impact factor: 1.848

Review 4.  Anti-vascular endothelial growth factor for prevention of postoperative vitreous cavity haemorrhage after vitrectomy for proliferative diabetic retinopathy.

Authors:  Jonathan M Smith; David H W Steel
Journal:  Cochrane Database Syst Rev       Date:  2015-08-07

5.  Multiple factors in the prediction of risk of recurrent vitreous haemorrhage after sutureless vitrectomy for non-clearing vitreous haemorrhage in patients with diabetic retinopathy.

Authors:  Yuhua Ding; Bangtao Yao; Hui Hang; Hui Ye
Journal:  BMC Ophthalmol       Date:  2020-07-16       Impact factor: 2.209

Review 6.  Current management of diabetic tractional retinal detachments.

Authors:  Michael W Stewart; David J Browning; Maurice B Landers
Journal:  Indian J Ophthalmol       Date:  2018-12       Impact factor: 1.848

  6 in total

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