Literature DB >> 24409211

Three primary testicular tumours: Trials and tribulations of testicular preservation.

Connor M Forbes1, Charles Metcalfe1, Nevin Murray2, Peter C Black1.   

Abstract

Balancing recurrence risk, side effects and patient preference in the treatment of multiple metachronous testicular tumours can be challenging. We present the case of a young male patient who developed 3 different primary testicular neoplasms over an 8-year period, each associated with retroperitoneal lymphadenopathy requiring chemotherapy. The first tumour at age 19 was managed with radical orchiectomy. Four years later, a partial orchiectomy was performed to remove 2 small lesions. Another 4 years later, a complete orchiectomy was required for an additional tumour. This case highlights the caveats of testis-sparing surgery for testis cancer and the need for careful surveillance in these patients.

Entities:  

Year:  2013        PMID: 24409211      PMCID: PMC3886200          DOI: 10.5489/cuaj.1260

Source DB:  PubMed          Journal:  Can Urol Assoc J        ISSN: 1911-6470            Impact factor:   1.862


  15 in total

Review 1.  Testicular germ cell tumors: biology and clinical update.

Authors:  Heather D Mannuel; Nirupama Mitikiri; Maleha Khan; Arif Hussain
Journal:  Curr Opin Oncol       Date:  2012-05       Impact factor: 3.645

Review 2.  Treatment of patients with relapsed and/or cisplatin-refractory metastatic germ cell tumours: an update.

Authors:  D Koychev; K Oechsle; C Bokemeyer; F Honecker
Journal:  Int J Androl       Date:  2011-08

Review 3.  Testicular microlithiasis predicts concurrent testicular germ cell tumors and intratubular germ cell neoplasia of unclassified type in adults: a meta-analysis and systematic review.

Authors:  Iain B Tan; Kai K Ang; Boon C Ching; Chandra Mohan; Chee K Toh; Min H Tan
Journal:  Cancer       Date:  2010-10-01       Impact factor: 6.860

4.  Management of disseminated nonseminomatous germ cell tumors with risk-based chemotherapy followed by response-guided postchemotherapy surgery.

Authors:  Christian Kollmannsberger; Siamak Daneshmand; Alan So; Kim N Chi; Nevin Murray; Christie Moore; Brandon Hayes-Lattin; Craig Nichols
Journal:  J Clin Oncol       Date:  2009-12-21       Impact factor: 44.544

5.  Partial orchiectomy for presumed malignancy in patients with a solitary testis due to a prior germ cell tumor: a large North American experience.

Authors:  Nathan Lawrentschuk; Alvaro Zuniga; Arthur C Grabowksi; Ricardo A Rendon; Michael A S Jewett
Journal:  J Urol       Date:  2010-12-17       Impact factor: 7.450

Review 6.  Increasing incidence of testicular cancer worldwide: a review.

Authors:  Eric Huyghe; Tomohiro Matsuda; Patrick Thonneau
Journal:  J Urol       Date:  2003-07       Impact factor: 7.450

Review 7.  Second malignant neoplasms in testicular cancer survivors.

Authors:  Chunkit Fung; Sophie D Fossa; Clair J Beard; Lois B Travis
Journal:  J Natl Compr Canc Netw       Date:  2012-04       Impact factor: 11.908

Review 8.  Organ-sparing approaches for testicular masses.

Authors:  Alvaro Zuniga; Nathan Lawrentschuk; Michael A S Jewett
Journal:  Nat Rev Urol       Date:  2010-08       Impact factor: 14.432

Review 9.  Testicular microlithiasis and carcinoma in situ overview and proposed clinical guideline.

Authors:  N J van Casteren; L H J Looijenga; G R Dohle
Journal:  Int J Androl       Date:  2008-12-22

10.  Risk and prognostic significance of metachronous contralateral testicular germ cell tumours.

Authors:  M Schaapveld; A W van den Belt-Dusebout; J A Gietema; R de Wit; S Horenblas; J A Witjes; H J Hoekstra; L A L M Kiemeney; W J Louwman; G M Ouwens; B M P Aleman; F E van Leeuwen
Journal:  Br J Cancer       Date:  2012-10-11       Impact factor: 7.640

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  2 in total

Review 1.  Fertility Risk Assessment and Preservation in Male and Female Prepubertal and Adolescent Cancer Patients.

Authors:  Nikolaos Zavras; Charalampos Siristatidis; Argyris Siatelis; Anna Koumarianou
Journal:  Clin Med Insights Oncol       Date:  2016-06-28

2.  Oncological and functional outcomes after testis-sparing surgery in patients with germ cell tumors: a systematic review of 285 cases.

Authors:  Josias Bastian Grogg; Zeynep Hafza Dursun; Joerg Beyer; Daniel Eberli; Cedric Poyet; Thomas Hermanns; Christian Daniel Fankhauser
Journal:  World J Urol       Date:  2022-07-12       Impact factor: 3.661

  2 in total

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