Literature DB >> 24408584

[Genetics of bovine lactate dehydrogenase isoenzymes].

K Frahm1, F Graf, H Kräußlich, L Furtmayr.   

Abstract

Instead of 5 usual isoenzyme bands of lactate dehydrogenase 15 bands were found in bloodserum of 75 cattle from different breeds using a special separation technique of polyacrylamid disc electrophoresis. -Because LDH-5 resolved in a total of 5 bands it was suggested that the 5 LDH isoenzymes are formed by 3 polypeptids BAA' which are under separate genetic control. With a simple genetical test it was demonstrated for the dairy herd examined (p < 0,001) that the genes controlling B, A and A' are placed on three independent loci and that there is no isoenzyme polymorphism. In 2 of 15 additionally checked waterbuffalos no resolving into 15bands was registrated, that means that a LDH-polymorphism probably may occur in buffalos.

Entities:  

Year:  1977        PMID: 24408584     DOI: 10.1007/BF00275168

Source DB:  PubMed          Journal:  Theor Appl Genet        ISSN: 0040-5752            Impact factor:   5.699


  8 in total

1.  Lactate dehydrogenase variant from human blood: evidence for molecular subunits.

Authors:  S H BOYER; D C FAINER; E J WATSON-WILLIAMS
Journal:  Science       Date:  1963-08-16       Impact factor: 47.728

2.  GENETIC EVIDENCE FOR THE SUBUNIT STRUCTURE OF LACTATE DEHYDROGENASE ISOZYMES.

Authors:  C R SHAW; E BARTO
Journal:  Proc Natl Acad Sci U S A       Date:  1963-08       Impact factor: 11.205

3.  Lactate Dehydrogenase Isozymes: Dissociation and Recombination of Subunits.

Authors:  C L Markert
Journal:  Science       Date:  1963-06-21       Impact factor: 47.728

4.  Separation and quantitation of lactic dehydrogenase isoenzymes by disc electrophoresis.

Authors:  A A Dietz; T Lubrano
Journal:  Anal Biochem       Date:  1967-08       Impact factor: 3.365

5.  Mutation at the A locus of lactate dehydrogenase in Holstein-Friesian cows.

Authors:  N Rauch
Journal:  Am J Vet Res       Date:  1971-09       Impact factor: 1.156

6.  Polymorphism of lactate dehydrogenase in gelada baboons.

Authors:  F N Syner; M Goodman
Journal:  Science       Date:  1966-01-14       Impact factor: 47.728

7.  A mutant form of lactate dehydrogenase in the horse.

Authors:  N Rauch
Journal:  Ann N Y Acad Sci       Date:  1968-06-14       Impact factor: 5.691

8.  Lactate dehydrogenase of trout: hybridization in vivo and in vitro.

Authors:  E Goldberg
Journal:  Science       Date:  1966-03-04       Impact factor: 47.728

  8 in total

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