Literature DB >> 2440811

The etiologic agents of leprosy and tuberculosis share an immunoreactive protein antigen with the vaccine strain Mycobacterium bovis BCG.

T M Shinnick, D Sweetser, J Thole, J van Embden, R A Young.   

Abstract

The amino acid sequences of the 65-kilodalton antigens of Mycobacterium leprae, Mycobacterium tuberculosis, and Mycobacterium bovis BCG display greater than 95% homology.

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Year:  1987        PMID: 2440811      PMCID: PMC260629          DOI: 10.1128/iai.55.8.1932-1935.1987

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  21 in total

1.  A conditional lethal mutation in an Escherichia coli strain with a longer chemical lifetime of messenger RNA.

Authors:  M Ono; M Kuwano
Journal:  J Mol Biol       Date:  1979-04-15       Impact factor: 5.469

2.  Cloning, sequence analysis, and expression of alteration of the mRNA stability gene (ams+) of Escherichia coli.

Authors:  P K Chanda; M Ono; M Kuwano; H Kung
Journal:  J Bacteriol       Date:  1985-01       Impact factor: 3.490

Review 3.  Leprosy and tuberculosis--an epidemiological comparison.

Authors:  P Fine
Journal:  Tubercle       Date:  1984-06

4.  Characteristics of human T-cell clones from BCG and killed M. leprae vaccinated subjects and tuberculosis patients. Recognition of recombinant mycobacterial antigens.

Authors:  A S Mustafa; F Oftung; H K Gill; I Natvig
Journal:  Lepr Rev       Date:  1986-12       Impact factor: 0.537

5.  Genes for the major protein antigens of the leprosy parasite Mycobacterium leprae.

Authors:  R A Young; V Mehra; D Sweetser; T Buchanan; J Clark-Curtiss; R W Davis; B R Bloom
Journal:  Nature       Date:  1985 Aug 1-7       Impact factor: 49.962

6.  Immunochemical characterization of a protein associated with Mycobacterium leprae cell wall.

Authors:  T P Gillis; R A Miller; D B Young; S R Khanolkar; T M Buchanan
Journal:  Infect Immun       Date:  1985-08       Impact factor: 3.441

7.  Production and characterization of monoclonal antibodies to Mycobacterium tuberculosis, M. bovis (BCG) and M. leprae.

Authors:  A H Kolk; M L Ho; P R Klatser; T A Eggelte; S Kuijper; S de Jonge; J van Leeuwen
Journal:  Clin Exp Immunol       Date:  1984-12       Impact factor: 4.330

8.  Cloning of Mycobacterium bovis BCG DNA and expression of antigens in Escherichia coli.

Authors:  J E Thole; H G Dauwerse; P K Das; D G Groothuis; L M Schouls; J D van Embden
Journal:  Infect Immun       Date:  1985-12       Impact factor: 3.441

9.  Monoclonal antibodies to a 28,000 mol. wt protein antigen of Mycobacterium leprae.

Authors:  D B Young; M J Fohn; S R Khanolkar; T M Buchanan
Journal:  Clin Exp Immunol       Date:  1985-06       Impact factor: 4.330

10.  Mycobacterium leprae antigens involved in human immune responses. I. Identification of four antigens by monoclonal antibodies.

Authors:  W J Britton; L Hellqvist; A Basten; R L Raison
Journal:  J Immunol       Date:  1985-12       Impact factor: 5.422

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  38 in total

1.  Encystation of Giardia lamblia leads to expression of antigens recognized by antibodies against conserved heat shock proteins.

Authors:  D S Reiner; T M Shinnick; F Ardeshir; F D Gillin
Journal:  Infect Immun       Date:  1992-12       Impact factor: 3.441

2.  Genes for immunodominant protein antigens are highly homologous in Mycobacterium tuberculosis, Mycobacterium africanum, and the vaccine strain Mycobacterium bovis BCG.

Authors:  M C Lu; M H Lien; R E Becker; H C Heine; A M Buggs; D Lipovsek; R Gupta; P W Robbins; C M Grosskinsky; S C Hubbard
Journal:  Infect Immun       Date:  1987-10       Impact factor: 3.441

3.  Mycobacterium paratuberculosis antigen D: characterization and evidence that it is a bacterioferritin.

Authors:  B W Brooks; N M Young; D C Watson; R H Robertson; E A Sugden; K H Nielsen; S A Becker
Journal:  J Clin Microbiol       Date:  1991-08       Impact factor: 5.948

Review 4.  Immunological study of the defined constituents of mycobacteria.

Authors:  J Ivanyi; K Sharp; P Jackett; G Bothamley
Journal:  Springer Semin Immunopathol       Date:  1988

5.  Cross-reactivity and sequence homology between the 65-kilodalton mycobacterial heat shock protein and human lactoferrin, transferrin, and DR beta subsets of major histocompatibility complex class II molecules.

Authors:  A Aguas; N Esaguy; C E Sunkel; M T Silva
Journal:  Infect Immun       Date:  1990-05       Impact factor: 3.441

6.  Mycobacterium tuberculosis expresses two chaperonin-60 homologs.

Authors:  T H Kong; A R Coates; P D Butcher; C J Hickman; T M Shinnick
Journal:  Proc Natl Acad Sci U S A       Date:  1993-04-01       Impact factor: 11.205

7.  Cellular immune responses of leprosy contacts to fractionated Mycobacterium leprae antigens.

Authors:  S P Lee; N G Stoker; K A Grant; Z T Handzel; R Hussain; K P McAdam; H M Dockrell
Journal:  Infect Immun       Date:  1989-08       Impact factor: 3.441

8.  Immunological characterization of a human homolog of the 65-kilodalton mycobacterial antigen.

Authors:  A K Dudani; R S Gupta
Journal:  Infect Immun       Date:  1989-09       Impact factor: 3.441

9.  Differentiation of slowly growing Mycobacterium species, including Mycobacterium tuberculosis, by gene amplification and restriction fragment length polymorphism analysis.

Authors:  B B Plikaytis; B D Plikaytis; M A Yakrus; W R Butler; C L Woodley; V A Silcox; T M Shinnick
Journal:  J Clin Microbiol       Date:  1992-07       Impact factor: 5.948

10.  Identification and characterization of epitopes shared between the mycobacterial 65-kilodalton heat shock protein and the actively secreted antigen 85 complex: their in situ expression on the cell wall surface of Mycobacterium leprae.

Authors:  A Rambukkana; P K Das; J D Burggraaf; W R Faber; P Teeling; S Krieg; J E Thole; M Harboe
Journal:  Infect Immun       Date:  1992-11       Impact factor: 3.441

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