Literature DB >> 24406510

Highly sensitive detection of telomerase using a telomere-triggered isothermal exponential amplification-based DNAzyme biosensor.

Yan Zhang1, Li-juan Wang, Chun-yang Zhang.   

Abstract

A telomere-triggered isothermal exponential amplification-based DNAzyme biosensor is developed for highly sensitive detection of telomerase in cancer cells even at the single-cell level. This biosensor can be further applied for the screening of telomerase inhibitors for anticancer drug development.

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Year:  2014        PMID： 24406510     DOI： 10.1039/c3cc48518h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  A PCR-free voltammetric telomerase activity assay using a substrate primer on a gold electrode and DNA-triggered capture of gold nanoparticles.

Authors:  Fanyu Meng; Yuanyuan Xu; Wenfei Dong; Yuguo Tang; Peng Miao
Journal:  Mikrochim Acta       Date:  2018-08-01       Impact factor: 5.833

Review 2.  Sensing telomerase: From in vitro detection to in vivo imaging.

Authors:  Li-Juan Wang; Fei Ma; Bo Tang; Chun-Yang Zhang
Journal:  Chem Sci       Date:  2016-12-13       Impact factor: 9.825

3.  Evaluation of intracellular telomerase activity through cascade DNA logic gates.

Authors:  Wenjing Wang; Shan Huang; Jingjing Li; Kai Rui; Sai Bi; Jian-Rong Zhang; Jun-Jie Zhu
Journal:  Chem Sci       Date:  2016-08-01       Impact factor: 9.825

4.  Cas9 cleavage assay for pre-screening of sgRNAs using nicking triggered isothermal amplification.

Authors:  Kaixiang Zhang; Ruijie Deng; Yue Li; Ling Zhang; Jinghong Li
Journal:  Chem Sci       Date:  2016-04-29       Impact factor: 9.825
  4 in total

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