PURPOSE: To investigate the subfoveal choroidal thickness in patients with retinal angiomatous proliferation (RAP). METHODS: In consecutive patients with RAP, subfoveal choroidal thickness was retrospectively measured by the use of enhanced depth imaging spectral domain optical coherence tomography in comparison with age-matched control subjects. RESULTS: Nineteen eyes of 19 patients with RAP and 32 eyes of 32 control subjects were included in this study. No significant differences were found between the eyes with RAP and the control eyes regarding age, gender, spherical equivalent, and axial length. Mean subfoveal choroidal thickness in 19 eyes with RAP was significantly less than that in the control eyes (129.5 ± 35.8 μm vs. 201.3 ± 55.0 μm, P < 0.0001). The difference in mean subfoveal choroidal thickness between eyes with Stage 2 RAP (132.8 ± 38.2 μm) and eyes with Stage 3 RAP (126.4 ± 36.6 μm) was not significant, though each measurement was significantly less than that in the control eyes (P < 0.001 and P = 0.002, respectively). CONCLUSION: Eyes with RAP had a significantly thinner subfoveal choroid compared with normal eyes. Such morphologic features may be related to the pathologic mechanism of RAP.
PURPOSE: To investigate the subfoveal choroidal thickness in patients with retinal angiomatous proliferation (RAP). METHODS: In consecutive patients with RAP, subfoveal choroidal thickness was retrospectively measured by the use of enhanced depth imaging spectral domain optical coherence tomography in comparison with age-matched control subjects. RESULTS: Nineteen eyes of 19 patients with RAP and 32 eyes of 32 control subjects were included in this study. No significant differences were found between the eyes with RAP and the control eyes regarding age, gender, spherical equivalent, and axial length. Mean subfoveal choroidal thickness in 19 eyes with RAP was significantly less than that in the control eyes (129.5 ± 35.8 μm vs. 201.3 ± 55.0 μm, P < 0.0001). The difference in mean subfoveal choroidal thickness between eyes with Stage 2 RAP (132.8 ± 38.2 μm) and eyes with Stage 3 RAP (126.4 ± 36.6 μm) was not significant, though each measurement was significantly less than that in the control eyes (P < 0.001 and P = 0.002, respectively). CONCLUSION: Eyes with RAP had a significantly thinner subfoveal choroid compared with normal eyes. Such morphologic features may be related to the pathologic mechanism of RAP.
Authors: Daniel Duck-Jin Hwang; Seong Choi; Junseo Ko; Jeewoo Yoon; Ji In Park; Joon Seo Hwang; Jeong Mo Han; Hak Jun Lee; Joonhong Sohn; Kyu Hyung Park; Jinyoung Han Journal: Sci Rep Date: 2021-04-29 Impact factor: 4.379
Authors: Jinyoung Han; Seong Choi; Ji In Park; Joon Seo Hwang; Jeong Mo Han; Hak Jun Lee; Junseo Ko; Jeewoo Yoon; Daniel Duck-Jin Hwang Journal: Sci Rep Date: 2022-02-09 Impact factor: 4.379