Nitin Joseph1, Deepak Madi2, Ganesh S Kumar3, Maria Nelliyanil4, Vittal Saralaya5, Sharada Rai6. 1. Department of Community Medicine, Kasturba Medical College, Manipal University, Mangalore, Karnataka, India. 2. Department of Internal Medicine, Kasturba Medical College, Manipal University, Mangalore, Karnataka, India. 3. Department of Community Medicine, JIPMER, Puducherry, India. 4. Department of Community Medicine, A J Institute of Medical Sciences and Research Centre, Mangalore, Karnataka, India. 5. Department of Obstetrics and Gynaecology, Kasturba Medical College, Manipal University, Mangalore, Karnataka, India. 6. Department of Pathology, Kasturba Medical College, Manipal University, Mangalore, Karnataka, India.
Abstract
BACKGROUND: Rheumatic fever (RF) is an important problem concerning developing countries like India. Rheumatic heart disease (RHD) is one of the most readily preventable chronic diseases. AIM: This study was done to find out the clinical profile, risk factors, compliance with treatment and outcome among RF/RHD cases so as to suggest better case management strategies. MATERIALS AND METHODS: Clinical records of 51 RF and 71 RHD cases admitted in tertiary care hospitals in Mangalore between 2001 and 2010 were reviewed retrospectively. RESULTS: Mean age of RF cases were 17.4 ± 12.1 years and RHD cases were 33.2 ± 18.6 years. More than half of RF and RHD cases were males. Commonest risk factors among RF cases were poor socioeconomic status (60.4%), history of upper respiratory tract infection before disease onset (58.8%) and undernutrition (35.3%). Commonest clinical manifestation among RF cases was fever 39 (76.5%) followed by polyarthritis 34 (66.7%). Commonest valvular lesions among RHD cases was mitral stenosis with mitral regurgitation found in 42.9% cases. Compliance of patients with prophylactic antibiotics was found to be 37 (30.3%). Mortality rate was significantly more among RHD cases (P = 0.0399). CONCLUSIONS: Improvement of socioeconomic and nutritional factors is an important task required for primary prophylaxis and of compliance for secondary prophylaxis of RF.
BACKGROUND:Rheumatic fever (RF) is an important problem concerning developing countries like India. Rheumatic heart disease (RHD) is one of the most readily preventable chronic diseases. AIM: This study was done to find out the clinical profile, risk factors, compliance with treatment and outcome among RF/RHD cases so as to suggest better case management strategies. MATERIALS AND METHODS: Clinical records of 51 RF and 71 RHD cases admitted in tertiary care hospitals in Mangalore between 2001 and 2010 were reviewed retrospectively. RESULTS: Mean age of RF cases were 17.4 ± 12.1 years and RHD cases were 33.2 ± 18.6 years. More than half of RF and RHD cases were males. Commonest risk factors among RF cases were poor socioeconomic status (60.4%), history of upper respiratory tract infection before disease onset (58.8%) and undernutrition (35.3%). Commonest clinical manifestation among RF cases was fever 39 (76.5%) followed by polyarthritis 34 (66.7%). Commonest valvular lesions among RHD cases was mitral stenosis with mitral regurgitation found in 42.9% cases. Compliance of patients with prophylactic antibiotics was found to be 37 (30.3%). Mortality rate was significantly more among RHD cases (P = 0.0399). CONCLUSIONS: Improvement of socioeconomic and nutritional factors is an important task required for primary prophylaxis and of compliance for secondary prophylaxis of RF.
Authors: Guilherme S Spina; Roney O Sampaio; Carlos E Branco; George B Miranda; Vitor E E Rosa; Flávio Tarasoutchi Journal: Front Pediatr Date: 2014-11-20 Impact factor: 3.418
Authors: Viorica Munteanu; Antonella Petaccia; Nicolae Contecaru; Emanuele Amodio; Carlo Virginio Agostoni Journal: AIMS Public Health Date: 2018-05-23