Literature DB >> 2440281

Experimental renal anaphylaxis: release of histamine and study of its effect on renal perfusion.

E S Assem, N A Abdullah.   

Abstract

Antigen challenge of isolated perfused kidneys of sensitized guinea-pigs consistently released a large proportion of their histamine content, and caused a reduction in renal perfusate flow rate (RPFR) which could not simply be due to the released histamine, since much larger amounts of exogenous histamine were needed to produce a comparable effect. Reduction in RPFR by histamine was blocked by mepyramine but not by cimetidine, i.e. it is mediated by an H1-receptor mechanism.

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Year:  1987        PMID: 2440281     DOI: 10.1007/bf02074695

Source DB:  PubMed          Journal:  Agents Actions        ISSN: 0065-4299


  9 in total

1.  Mechanisms of action of hisamine and histamine antagonists on the glomerular microcirculation in the rat.

Authors:  I Ichikawa; B M Brenner
Journal:  Circ Res       Date:  1979-12       Impact factor: 17.367

2.  Mast cells in human kidney cortex.

Authors:  T Saruta; K Kondo; T Ohguro; Y Ozawa; E Kato
Journal:  Keio J Med       Date:  1977-11

3.  Effect of histamine and antihistamines on renal hemodynamics and functions in the isolated perfused canine kidney.

Authors:  W B Campbell; H D Itskovitz
Journal:  J Pharmacol Exp Ther       Date:  1976-09       Impact factor: 4.030

4.  Basophil sensitisation in idiopathic nephrotic syndrome.

Authors:  E Pirotzky; C Hieblot; J Benveniste; J Laurent; G Lagrue; C Noirot
Journal:  Lancet       Date:  1982-02-13       Impact factor: 79.321

5.  Release of platelet-activating factor, slow-reacting substance, and vasoactive amines from isolated rat kidneys.

Authors:  E Pirotzky; J Bidault; C Burtin; M C Gubler; J Benveniste
Journal:  Kidney Int       Date:  1984-02       Impact factor: 10.612

6.  Actions and metabolism of histamine in glomeruli and tubules of the human kidney.

Authors:  J R Sedor; H E Abboud
Journal:  Kidney Int       Date:  1984-08       Impact factor: 10.612

7.  Release of thromboxane B2 and leukotriene C4 and reduction in renal perfusion in experimental anaphylactic reaction of isolated guinea pig kidney.

Authors:  E S Assem; N A Abdullah
Journal:  Int Arch Allergy Appl Immunol       Date:  1987

8.  Severe steroid-responsive nephrosis associated with hypersensitivity.

Authors:  D H Sandberg; C W Bernstein; R M McIntosh; R Carr; J Strauss
Journal:  Lancet       Date:  1977-02-19       Impact factor: 79.321

9.  Renal histamine: release by immune stimuli.

Authors:  E S Assem; N A Abdullah; N S Ghanem
Journal:  Agents Actions       Date:  1986-11
  9 in total
  3 in total

1.  Immune release of histamine and other lipid mediators from guinea-pig isolated kidney: antagonism by BN-52021.

Authors:  F Berti; G Rossoni; P Braquet
Journal:  Agents Actions       Date:  1990-06

2.  Role of thromboxane A2, leukotriene C4 and histamine in the antigen-induced vasoconstriction in perfused, sensitized guinea-pig kidney.

Authors:  N A Abdullah; E S Assem
Journal:  Agents Actions       Date:  1989-04

3.  Anaphylatoxin-induced release of histamine from in vitro perfused guinea pig kidney.

Authors:  N A Abdullah; E S Assem; B Damerau
Journal:  Agents Actions       Date:  1988-04
  3 in total

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