Literature DB >> 2440196

Glutaraldehyde inactivated pertussis vaccine: a safe vaccine in the innocuity test.

R K Gupta, S B Sharma, S Ahuja, S N Saxena.   

Abstract

The adsorbed diphtheria-pertussis-tetanus (DPT) vaccine containing glutaraldehyde inactivated pertussis vaccine passed the innocuity test only after one month's storage of the preparation at 4-8 degrees C when the adsorbed DPT vaccine containing pertussis vaccine inactivated by heat, formaldehyde, thimerosal or acetone did not pass the test. The adsorbed DPT vaccine became innocuous when it was stored at 4-8 degrees C. The innocuity test was passed more easily in guinea pigs than in mice.

Entities:  

Mesh:

Substances:

Year:  1987        PMID: 2440196     DOI: 10.1016/0264-410x(87)90054-5

Source DB:  PubMed          Journal:  Vaccine        ISSN: 0264-410X            Impact factor:   3.641


  2 in total

1.  Thermostability of Well-Ordered HIV Spikes Correlates with the Elicitation of Autologous Tier 2 Neutralizing Antibodies.

Authors:  Yu Feng; Karen Tran; Shridhar Bale; Shailendra Kumar; Javier Guenaga; Richard Wilson; Natalia de Val; Heather Arendt; Joanne DeStefano; Andrew B Ward; Richard T Wyatt
Journal:  PLoS Pathog       Date:  2016-08-03       Impact factor: 6.823

2.  Study on Toxicity Reduction and Potency Induction in Whole-cell Pertussis Vaccine by Developing a New Optimal Inactivation Condition Processed on Bordetella pertussis.

Authors:  Naser Mohammadpour Dounighi; Mehdi Razzaghi-Abyane; Mojtaba Nofeli; Hossein Zolfagharian; Fereshteh Shahcheraghi
Journal:  Jundishapur J Microbiol       Date:  2016-07-09       Impact factor: 0.747

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.