Literature DB >> 24400908

Conversion of oxazolidinediones to isoindoloisoquinolinones via intramolecular Friedel–Crafts reaction.

Ji-Young Min, Guncheol Kim.   

Abstract

Treatment of oxazolidinediones with TiCl4 in CH2Cl2 resulted in conversion to isoindoloisoquinolinones via intramolecular Friedel–Crafts reaction with extrusion of CO2 in the transformation. The alkaloid nuevamine has been synthesized under these conditions in a regiospecific manner.

Entities:  

Year:  2014        PMID： 24400908     DOI： 10.1021/jo402345q

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  2 in total

1.  Influence of ligand geometry on cholinesterase enzyme - A comparison of 1-isoindolinone based structural analog with Donepezil.

Authors:  Sunil P Upadhyay; Vikas Singh; Ram Sharma; Jianping Zhou; Pritam Thapa; David K Johnson; Andrew Keightley; Maohui Chen; William Suo; Mukut Sharma
Journal:  J Mol Struct       Date:  2021-08-31       Impact factor: 3.841

2.  Chiral Brønsted Acid-Catalyzed Enantioselective α-Amidoalkylation Reactions: A Joint Experimental and Predictive Study.

Authors:  Eider Aranzamendi; Sonia Arrasate; Nuria Sotomayor; Humberto González-Díaz; Esther Lete
Journal:  ChemistryOpen       Date:  2016-11-23       Impact factor: 2.911
  2 in total

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