Literature DB >> 2439914

A new T-cell receptor gene located within the alpha locus and expressed early in T-cell differentiation.

Y H Chien, M Iwashima, K B Kaplan, J F Elliott, M M Davis.   

Abstract

A new T-cell receptor gene lies just 5' to the J alpha C alpha coding regions. Its placement in this location suggests a novel mechanism for the regulation of expression of one T-cell receptor polypeptide to another during ontogeny. Rearrangement of this locus occurs very early in thymic differentiation and its RNA expression parallels that of the gamma-chain in thymic subpopulations, making this a possible candidate for the recently described delta-chain of the T-cell receptor.

Mesh:

Substances:

Year:  1987        PMID: 2439914     DOI: 10.1038/327677a0

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  129 in total

1.  High-density genome scan in Crohn disease shows confirmed linkage to chromosome 14q11-12.

Authors:  R H Duerr; M M Barmada; L Zhang; R Pfützer; D E Weeks
Journal:  Am J Hum Genet       Date:  2000-04-03       Impact factor: 11.025

Review 2.  Receptor selection in B and T lymphocytes.

Authors:  D Nemazee
Journal:  Annu Rev Immunol       Date:  2000       Impact factor: 28.527

Review 3.  Tissue distribution, antigen specificity and effector functions of gamma delta T cells in human diseases.

Authors:  G De Libero
Journal:  Springer Semin Immunopathol       Date:  2000

Review 4.  Antigen recognition by human gamma delta T cells: pattern recognition by the adaptive immune system.

Authors:  C T Morita; R A Mariuzza; M B Brenner
Journal:  Springer Semin Immunopathol       Date:  2000

Review 5.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

6.  Transcription of germ line V alpha segments correlates with ongoing T-cell receptor alpha-chain rearrangement.

Authors:  J D Fondell; K B Marcu
Journal:  Mol Cell Biol       Date:  1992-04       Impact factor: 4.272

Review 7.  Mouse chromosome 14.

Authors:  J H Nadeau; R Cox
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

8.  Sequence and expression of a novel human T-cell receptor beta-chain variable gene segment subfamily.

Authors:  R K Wilson; E Lai; L D Kim; L Hood
Journal:  Immunogenetics       Date:  1990       Impact factor: 2.846

9.  Expression of T-cell receptor alpha-chain genes in transgenic mice.

Authors:  L J Berg; B Fazekas de St Groth; F Ivars; C C Goodnow; S Gilfillan; H J Garchon; M M Davis
Journal:  Mol Cell Biol       Date:  1988-12       Impact factor: 4.272

Review 10.  A cold-blooded view of adaptive immunity.

Authors:  Martin F Flajnik
Journal:  Nat Rev Immunol       Date:  2018-07       Impact factor: 53.106

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.