| Literature DB >> 2439914 |
Y H Chien, M Iwashima, K B Kaplan, J F Elliott, M M Davis.
Abstract
A new T-cell receptor gene lies just 5' to the J alpha C alpha coding regions. Its placement in this location suggests a novel mechanism for the regulation of expression of one T-cell receptor polypeptide to another during ontogeny. Rearrangement of this locus occurs very early in thymic differentiation and its RNA expression parallels that of the gamma-chain in thymic subpopulations, making this a possible candidate for the recently described delta-chain of the T-cell receptor.Mesh:
Substances:
Year: 1987 PMID: 2439914 DOI: 10.1038/327677a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962