Literature DB >> 24398961

The many faces of sirtuins: Sirtuins and the Warburg effect.

Leonard Guarente1.   

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Year:  2014        PMID： 24398961     DOI： 10.1038/nm.3438

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


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  15 in total

1.  Activation of the protein deacetylase SIRT6 by long-chain fatty acids and widespread deacylation by mammalian sirtuins.

Authors:  Jessica L Feldman; Josue Baeza; John M Denu
Journal:  J Biol Chem       Date:  2013-09-18       Impact factor: 5.157

Review 2.  Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling.

Authors:  Eric Verdin; Matthew D Hirschey; Lydia W S Finley; Marcia C Haigis
Journal:  Trends Biochem Sci       Date:  2010-09-20       Impact factor: 13.807

3.  SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells.

Authors:  Marcia C Haigis; Raul Mostoslavsky; Kevin M Haigis; Kamau Fahie; Danos C Christodoulou; Andrew J Murphy; David M Valenzuela; George D Yancopoulos; Margaret Karow; Gil Blander; Cynthia Wolberger; Tomas A Prolla; Richard Weindruch; Frederick W Alt; Leonard Guarente
Journal:  Cell       Date:  2006-09-08       Impact factor: 41.582

4.  SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization.

Authors:  Lydia W S Finley; Arkaitz Carracedo; Jaewon Lee; Amanda Souza; Ainara Egia; Jiangwen Zhang; Julie Teruya-Feldstein; Paula I Moreira; Sandra M Cardoso; Clary B Clish; Pier Paolo Pandolfi; Marcia C Haigis
Journal:  Cancer Cell       Date:  2011-03-08       Impact factor: 31.743

5.  SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress.

Authors:  Hyun-Seok Kim; Krish Patel; Kristi Muldoon-Jacobs; Kheem S Bisht; Nukhet Aykin-Burns; J Daniel Pennington; Riet van der Meer; Phuongmai Nguyen; Jason Savage; Kjerstin M Owens; Athanassios Vassilopoulos; Ozkan Ozden; Seong-Hoon Park; Keshav K Singh; Sarki A Abdulkadir; Douglas R Spitz; Chu-Xia Deng; David Gius
Journal:  Cancer Cell       Date:  2010-01-19       Impact factor: 31.743

Review 6.  Targeting the PI3K signaling pathway in cancer.

Authors:  Kwok-Kin Wong; Jeffrey A Engelman; Lewis C Cantley
Journal:  Curr Opin Genet Dev       Date:  2009-12-16       Impact factor: 5.578

7.  Evidence for a common mechanism of SIRT1 regulation by allosteric activators.

Authors:  Basil P Hubbard; Ana P Gomes; Han Dai; Jun Li; April W Case; Thomas Considine; Thomas V Riera; Jessica E Lee; Sook Yen E; Dudley W Lamming; Bradley L Pentelute; Eli R Schuman; Linda A Stevens; Alvin J Y Ling; Sean M Armour; Shaday Michan; Huizhen Zhao; Yong Jiang; Sharon M Sweitzer; Charles A Blum; Jeremy S Disch; Pui Yee Ng; Konrad T Howitz; Anabela P Rolo; Yoshitomo Hamuro; Joel Moss; Robert B Perni; James L Ellis; George P Vlasuk; David A Sinclair
Journal:  Science       Date:  2013-03-08       Impact factor: 47.728

8.  The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4.

Authors:  Alfred Csibi; Sarah-Maria Fendt; Chenggang Li; George Poulogiannis; Andrew Y Choo; Douglas J Chapski; Seung Min Jeong; Jamie M Dempsey; Andrey Parkhitko; Tasha Morrison; Elizabeth P Henske; Marcia C Haigis; Lewis C Cantley; Gregory Stephanopoulos; Jane Yu; John Blenis
Journal:  Cell       Date:  2013-05-09       Impact factor: 41.582

9.  THE METABOLISM OF TUMORS IN THE BODY.

Authors:  O Warburg; F Wind; E Negelein
Journal:  J Gen Physiol       Date:  1927-03-07       Impact factor: 4.086

Review 10.  Calorie restriction and sirtuins revisited.

Authors:  Leonard Guarente
Journal:  Genes Dev       Date:  2013-10-01       Impact factor: 11.361
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  16 in total

Review 1.  Metabolic modulation of cancer: a new frontier with great translational potential.

Authors:  Adam Kinnaird; Evangelos D Michelakis
Journal:  J Mol Med (Berl)       Date:  2015-01-14       Impact factor: 4.599

Review 2.  Interplay Between SIRT-3, Metabolism and Its Tumor Suppressor Role in Hepatocellular Carcinoma.

Authors:  Serena De Matteis; Anna Maria Granato; Roberta Napolitano; Chiara Molinari; Martina Valgiusti; Daniele Santini; Francesco Giuseppe Foschi; Giorgio Ercolani; Umberto Vespasiani Gentilucci; Luca Faloppi; Mario Scartozzi; Giovanni Luca Frassineti; Andrea Casadei Gardini
Journal:  Dig Dis Sci       Date:  2017-05-19       Impact factor: 3.199

3.  The sirtuin family in cancer.

Authors:  Luis Filipe Costa-Machado; Pablo J Fernandez-Marcos
Journal:  Cell Cycle       Date:  2019-07-25       Impact factor: 4.534

4.  SIRT2-Mediated Deacetylation and Tetramerization of Pyruvate Kinase Directs Glycolysis and Tumor Growth.

Authors:  Seong-Hoon Park; Ozkan Ozden; Guoxiang Liu; Ha Yong Song; Yueming Zhu; Yufan Yan; Xianghui Zou; Hong-Jun Kang; Haiyan Jiang; Daniel R Principe; Yong-Il Cha; Meejeon Roh; Athanassios Vassilopoulos; David Gius
Journal:  Cancer Res       Date:  2016-04-27       Impact factor: 12.701

5.  Loss of NAD-Dependent Protein Deacetylase Sirtuin-2 Alters Mitochondrial Protein Acetylation and Dysregulates Mitophagy.

Authors:  Guoxiang Liu; Seong-Hoon Park; Marta Imbesi; William Joseph Nathan; Xianghui Zou; Yueming Zhu; Haiyan Jiang; Loukia Parisiadou; David Gius
Journal:  Antioxid Redox Signal       Date:  2016-09-08       Impact factor: 8.401

Review 6.  Is nuclear sirtuin SIRT6 a master regulator of immune function?

Authors:  Vinodkumar B Pillai; Mahesh P Gupta
Journal:  Am J Physiol Endocrinol Metab       Date:  2020-12-14       Impact factor: 4.310

7.  SIRT1 affects DNA methylation of polycomb group protein target genes, a hotspot of the epigenetic shift observed in ageing.

Authors:  Luisa A Wakeling; Laura J Ions; Suzanne M Escolme; Simon J Cockell; Tianhong Su; Madhurima Dey; Emily V Hampton; Gail Jenkins; Linda J Wainwright; Jill A McKay; Dianne Ford
Journal:  Hum Genomics       Date:  2015-06-24       Impact factor: 4.639

8.  Upregulation of mitochondrial NAD+ levels impairs the clonogenicity of SSEA1+ glioblastoma tumor-initiating cells.

Authors:  Myung Jin Son; Jae-Sung Ryu; Jae Yun Kim; Youjeong Kwon; Kyung-Sook Chung; Seon Ju Mun; Yee Sook Cho
Journal:  Exp Mol Med       Date:  2017-06-09       Impact factor: 8.718

9.  Mechanism of inhibition of the human sirtuin enzyme SIRT3 by nicotinamide: computational and experimental studies.

Authors:  Xiangying Guan; Ping Lin; Eric Knoll; Raj Chakrabarti
Journal:  PLoS One       Date:  2014-09-15       Impact factor: 3.240

Review 10.  Progress in aptamer-mediated drug delivery vehicles for cancer targeting and its implications in addressing chemotherapeutic challenges.

Authors:  Jie Zhu; He Huang; Shiwu Dong; Liang Ge; Yuan Zhang
Journal:  Theranostics       Date:  2014-07-13       Impact factor: 11.556
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