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Literature DB >> 24398957

Good guys gone bad: exTreg cells promote autoimmune arthritis.

Nicole Joller¹, Vijay K Kuchroo¹.

Abstract

Entities: Disease

Mesh：

Substances：

Year: 2014 PMID： 24398957 DOI： 10.1038/nm.3439

Source DB: PubMed Journal: Nat Med ISSN： 1078-8956 Impact factor: 53.440

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16 in total

1. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells.

Authors: Estelle Bettelli; Yijun Carrier; Wenda Gao; Thomas Korn; Terry B Strom; Mohamed Oukka; Howard L Weiner; Vijay K Kuchroo
Journal: Nature Date: 2006-04-30 Impact factor: 49.962

2. Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3.

Authors: Luke M Williams; Alexander Y Rudensky
Journal: Nat Immunol Date: 2007-01-14 Impact factor: 25.606

3. T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development.

Authors: Naganari Ohkura; Masahide Hamaguchi; Hiromasa Morikawa; Kyoko Sugimura; Atsushi Tanaka; Yoshinaga Ito; Motonao Osaki; Yoshiaki Tanaka; Riu Yamashita; Naoko Nakano; Jochen Huehn; Hans Joerg Fehling; Tim Sparwasser; Kenta Nakai; Shimon Sakaguchi
Journal: Immunity Date: 2012-11-01 Impact factor: 31.745

4. Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation.

Authors: Thomas Korn; Jayagopala Reddy; Wenda Gao; Estelle Bettelli; Amit Awasthi; Troels R Petersen; B Thomas Bäckström; Raymond A Sobel; Kai W Wucherpfennig; Terry B Strom; Mohamed Oukka; Vijay K Kuchroo
Journal: Nat Med Date: 2007-03-25 Impact factor: 53.440

5. Self-antigen-driven activation induces instability of regulatory T cells during an inflammatory autoimmune response.

Authors: Samantha L Bailey-Bucktrout; Marc Martinez-Llordella; Xuyu Zhou; Bryan Anthony; Wendy Rosenthal; Herve Luche; Hans J Fehling; Jeffrey A Bluestone
Journal: Immunity Date: 2013-11-14 Impact factor: 31.745

6. Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis.

Authors: Noriko Komatsu; Kazuo Okamoto; Shinichiro Sawa; Tomoki Nakashima; Masatsugu Oh-hora; Tatsuhiko Kodama; Sakae Tanaka; Jeffrey A Bluestone; Hiroshi Takayanagi
Journal: Nat Med Date: 2013-12-22 Impact factor: 53.440

7. Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis.

Authors: Hong Nie; Yingxia Zheng; Runsheng Li; Taylor B Guo; Dongyi He; Lei Fang; Xuebin Liu; Lianbo Xiao; Xi Chen; Bing Wan; Y Eugene Chin; Jingwu Z Zhang
Journal: Nat Med Date: 2013-02-10 Impact factor: 53.440

8. CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner.

Authors: Ashutosh Chaudhry; Dipayan Rudra; Piper Treuting; Robert M Samstein; Yuqiong Liang; Arnold Kas; Alexander Y Rudensky
Journal: Science Date: 2009-10-01 Impact factor: 47.728

9. Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells.

Authors: Takahisa Miyao; Stefan Floess; Ruka Setoguchi; Hervé Luche; Hans Joerg Fehling; Herman Waldmann; Jochen Huehn; Shohei Hori
Journal: Immunity Date: 2012-02-09 Impact factor: 31.745

10. Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo.

Authors: Xuyu Zhou; Samantha L Bailey-Bucktrout; Lukas T Jeker; Cristina Penaranda; Marc Martínez-Llordella; Meredith Ashby; Maki Nakayama; Wendy Rosenthal; Jeffrey A Bluestone
Journal: Nat Immunol Date: 2009-07-26 Impact factor: 25.606

10 in total

1. Paradoxical Expansion of Th1 and Th17 Lymphocytes in Rheumatoid Arthritis Following Infliximab Treatment: a Possible Explanation for a Lack of Clinical Response.

Authors: Rossella Talotta; Angela Berzi; Fabiola Atzeni; Alberto Batticciotto; Mario Clerici; Piercarlo Sarzi-Puttini; Daria Trabattoni
Journal: J Clin Immunol Date: 2015-08-14 Impact factor: 8.317

2. The transcriptional repressor Bcl6 controls the stability of regulatory T cells by intrinsic and extrinsic pathways.

Authors: Deepali V Sawant; Hao Wu; Weiguo Yao; Sarita Sehra; Mark H Kaplan; Alexander L Dent
Journal: Immunology Date: 2015-05 Impact factor: 7.397

Review 3. The Role of Chemokines in Shaping the Balance Between CD4(+) T Cell Subsets and Its Therapeutic Implications in Autoimmune and Cancer Diseases.

Authors: Nathan Karin; Gizi Wildbaum
Journal: Front Immunol Date: 2015-11-30 Impact factor: 7.561

Review 4. Mechanisms of exTreg induction.

Authors: Vikas Saxena; Ram Lakhan; Jegan Iyyathurai; Jonathan S Bromberg
Journal: Eur J Immunol Date: 2021-05-27 Impact factor: 6.688

5. Treg tissue stability depends on lymphotoxin beta-receptor- and adenosine-receptor-driven lymphatic endothelial cell responses.

Authors: Vikas Saxena; Wenji Piao; Lushen Li; Christina Paluskievicz; Yanbao Xiong; Thomas Simon; Ram Lakhan; C Colin Brinkman; Sarah Walden; Keli L Hippen; Marina WillsonShirkey; Young S Lee; Chelsea Wagner; Bruce R Blazar; Jonathan S Bromberg
Journal: Cell Rep Date: 2022-04-19 Impact factor: 9.995

Good guys gone bad: exTreg cells promote autoimmune arthritis.

1. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells.

2. Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3.

3. T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development.

4. Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation.

5. Self-antigen-driven activation induces instability of regulatory T cells during an inflammatory autoimmune response.

6. Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis.

7. Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis.

8. CD4+ regulatory T cells control TH17 responses in a Stat3-dependent manner.

9. Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells.

10. Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo.

1. Paradoxical Expansion of Th1 and Th17 Lymphocytes in Rheumatoid Arthritis Following Infliximab Treatment: a Possible Explanation for a Lack of Clinical Response.

2. The transcriptional repressor Bcl6 controls the stability of regulatory T cells by intrinsic and extrinsic pathways.

Review 3. The Role of Chemokines in Shaping the Balance Between CD4(+) T Cell Subsets and Its Therapeutic Implications in Autoimmune and Cancer Diseases.

Review 4. Mechanisms of exTreg induction.

5. Treg tissue stability depends on lymphotoxin beta-receptor- and adenosine-receptor-driven lymphatic endothelial cell responses.

Review 6. Restoring the balance: immunotherapeutic combinations for autoimmune disease.

Review 7. IL-17A-Producing Foxp3⁺ Regulatory T Cells and Human Diseases.

Review 8. Vitamin D as a Potential Therapy for Multiple Sclerosis: Where Are We?

9. Repertoire analyses reveal T cell antigen receptor sequence features that influence T cell fate.

Review 10. Regulatory T Cells in Respiratory Health and Diseases.

Review 3. The Role of Chemokines in Shaping the Balance Between CD4(+) T Cell Subsets and Its Therapeutic Implications in Autoimmune and Cancer Diseases.

Review 4. Mechanisms of exTreg induction.

Review 6. Restoring the balance: immunotherapeutic combinations for autoimmune disease.

Review 7. IL-17A-Producing Foxp3+ Regulatory T Cells and Human Diseases.

Review 8. Vitamin D as a Potential Therapy for Multiple Sclerosis: Where Are We?

Review 10. Regulatory T Cells in Respiratory Health and Diseases.

Review 7. IL-17A-Producing Foxp3⁺ Regulatory T Cells and Human Diseases.