| Literature DB >> 24397993 |
Liyan Yu1, Fuxian Zhang2, Zhijuan Hu1, Hui Ding1, Huifang Tang3, Zhongjun Ma4, Xiaofeng Zhao5.
Abstract
A new prenylated chalcone xanthohumol M (1), a novel prenylated bichalcone humulusol (2) and six known chalcones (3-8) were found from Humulus lupulus. Their structures were determined by spectroscopic methods. All the chalcones' electrophilic abilities were assessed by GSH (glutathione) rapid screening, and their QR (quinone reductase) induction activities were evaluated using hepa 1c1c7 cells. The results of electrophilic assay and QR induction activity assay were quite well. New compounds 1 and 2, along with some known prenylated chalcones, displayed certain QR induction activity.Entities:
Keywords: Electrophilic; Humulusol; Prenylated chalcone; QR induction; Xanthohumol M
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Year: 2014 PMID： 24397993 DOI： 10.1016/j.fitote.2013.12.019
Source DB: PubMed Journal: Fitoterapia ISSN： 0367-326X Impact factor: 2.882