Literature DB >> 24395323

Giant cell tumour of the proximal femur: Is joint-sparing management ever successful?

A E Wijsbek1, B L Vazquez-Garcia, R J Grimer, S R Carter, A A Abudu, R M Tillman, L Jeys.   

Abstract

The purpose of this study was to assess whether the use of a joint-sparing technique such as curettage and grafting was successful in eradicating giant cell tumours of the proximal femur, or whether an alternative strategy was more appropriate. Between 1974 and 2012, 24 patients with a giant cell tumour of the proximal femur were treated primarily at our hospital. Treatment was either joint sparing or joint replacing. Joint-sparing treatment was undertaken in ten patients by curettage with or without adjunctive bone graft. Joint replacement was by total hip replacement in nine patients and endoprosthetic replacement in five. All 11 patients who presented with a pathological fracture were treated by replacement. Local recurrence occurred in five patients (21%): two were treated by hip replacement, three by curettage and none with an endoprosthesis. Of the ten patients treated initially by curettage, six had a successful outcome without local recurrence and required no further surgery. Three eventually needed a hip replacement for local recurrence and one an endoprosthetic replacement for mechanical failure. Thus 18 patients had the affected joint replaced and only six (25%) retained their native joint. Overall, 60% of patients without a pathological fracture who were treated with curettage had a successful outcome.

Entities:  

Keywords:  Bone tumour; Curettage; Endoprosthesis; Giant cell tumour; Pathological fracture; Proximal femur

Mesh:

Year:  2014        PMID: 24395323     DOI: 10.1302/0301-620X.96B1.31763

Source DB:  PubMed          Journal:  Bone Joint J        ISSN: 2049-4394            Impact factor:   5.082


  9 in total

1.  Surgical strategy for benign lesions in proximal femur: internal fixation or endoprosthetic replacement.

Authors:  Hongyuan Liu; Xiang Fang; Zeping Yu; Yun Lang; Yan Xiong; Hong Duan
Journal:  Int Orthop       Date:  2018-04-17       Impact factor: 3.075

2.  Higher local recurrence rates after intralesional surgery for giant cell tumor of the proximal femur compared to other sites.

Authors:  Costantino Errani; Shinji Tsukamoto; Giulio Leone; Manabu Akahane; Luca Cevolani; Piergiuseppe Tanzi; Akira Kido; Kanya Honoki; Yasuhito Tanaka; Davide Maria Donati
Journal:  Eur J Orthop Surg Traumatol       Date:  2017-06-06

3.  En Bloc Resection of Giant Cell Tumor following Neoadjuvant Denosumab: A Case Report and Review of the Literature.

Authors:  Sarah C Tepper; Ari M Spellman; Charles A Gusho; Alan T Blank
Journal:  Orthop Rev (Pavia)       Date:  2022-05-31

4.  Risk factors of fracture following curettage for bone giant cell tumors of the extremities.

Authors:  Shinji Tsukamoto; Andreas F Mavrogenis; Manabu Akahane; Kanya Honoki; Akira Kido; Yasuhito Tanaka; Davide Maria Donati; Costantino Errani
Journal:  BMC Musculoskelet Disord       Date:  2022-05-19       Impact factor: 2.562

Review 5.  Present day controversies and consensus in curettage for giant cell tumor of bone.

Authors:  Costantino Errani; Shinji Tsukamoto; Giovanni Ciani; Davide Maria Donati
Journal:  J Clin Orthop Trauma       Date:  2019-10-11

6.  Giant cell tumour of the femoral neck: Failure of curettage-cavity filling cementation with screw fixation, a case report.

Authors:  S Abdulrazak; A Marzouki; S T Bah; K Lahrach; F Boutayeb
Journal:  Trauma Case Rep       Date:  2019-06-21

7.  Comparative Analysis of Two Surgical Treatment Options for Giant Cell Tumor of the Proximal Femur: Extended Curettage and Segmental Resection.

Authors:  Yuhao Yuan; Qing Liu; Yupeng Liu; Ziyi Wu; Wei Zhong; Hongbo He; Wei Luo
Journal:  Front Oncol       Date:  2021-12-20       Impact factor: 6.244

8.  Giant Cell Tumor of the Femoral Head: A Case Report and Review of the Literature.

Authors:  Hany Elbardesy; G A Sheridan; S Guerin
Journal:  J Orthop Case Rep       Date:  2021-05

9.  Surgical treatment of benign osteolytic lesions in the femoral head and neck: a systematic review.

Authors:  Jingtian Shi; Zhiqing Zhao; Taiqiang Yan; Wei Guo; Rongli Yang; Xiaodong Tang; Huayi Qu; Sen Dong
Journal:  BMC Musculoskelet Disord       Date:  2021-06-16       Impact factor: 2.362

  9 in total

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