Literature DB >> 24394120

[Case of a patient with inflammatory breast cancer who responded to preoperative chemotherapy with paclitaxel plus bevacizumab and could subsequently undergo surgery].

Shinichiro Kashiwagi1, Sae Ishihara, Mariko Ishii, Yuka Asano, Mao Watanabe, Tamami Morisaki, Naoki Aomatsu, Satoru Noda, Hidemi Kawajiri, Taeko Nakano, Noriko Kawakami, Yasuko Mitsukawa, Tsutomu Takashima, Naoyoshi Onoda, Tetsuro Ishikawa, Kosei Hirakawa.   

Abstract

A 58-year-old woman observed swelling in her left breast a few weeks prior to presentation. Rigidity in the D area, breast warmth, swelling, and a peau d'orange appearance in the whole left breast was observed. She was diagnosed with inflammatory breast cancer (luminal A type) T4dN2M0, Stage IIIB. The patient underwent primary systemic therapy with 7 courses of FEC. Following FEC treatment, the disease was stable. We subsequently administered 4 courses of bevacizumab plus paclitaxel combination therapy. The patient exhibited a partial response to FEC chemotherapy. Thereafter, a left mastectomy with level II axillary lymph node dissection was performed. At present, 1 year after surgery, the patient is alive with no recurrence. We conclude that the combination therapy of bevacizumab plus paclitaxel is a useful treatment for inflammatory breast cancer.

Entities:  

Mesh:

Substances:

Year:  2013        PMID: 24394120

Source DB:  PubMed          Journal:  Gan To Kagaku Ryoho        ISSN: 0385-0684


  2 in total

1.  Effectiveness of Pertuzumab, Trastuzumab, and Docetaxel Combination Neoadjuvant Chemotherapy for HER2-Positive Inflammatory Breast Cancer: A Case Report.

Authors:  Yuji Yamashita; Yuko Tanaka; Seishi Kono; Meiko Nishimura; Toru Mukohara; Yukiko Morinaga; Shigeo Hara; Shintaro Takao
Journal:  Breast Care (Basel)       Date:  2017-02-28       Impact factor: 2.860

2.  Literature-Wide Association Studies (LWAS) for a Rare Disease: Drug Repurposing for Inflammatory Breast Cancer.

Authors:  Xiaojia Ji; Chunming Jin; Xialan Dong; Maria S Dixon; Kevin P Williams; Weifan Zheng
Journal:  Molecules       Date:  2020-08-28       Impact factor: 4.411

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.