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Literature DB >> 2439372

Monoclonal antibody to fibronectin which inhibits extracellular matrix assembly.

M A Chernousov, A I Faerman, M G Frid, V E Koteliansky.

Abstract

A monoclonal antibody L8 specific to fibronectin was shown to inhibit fibronectin incorporation into the fibroblast extracellular matrix. Antibody L8 could not interact with fibronectin complexed with gelatin. The results suggest the existence of a specific site on the fibronectin molecule playing a critical role in the assembly of the fibronectin extracellular matrix. This site is located near the collagen-binding domain.

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Year: 1987 PMID： 2439372 DOI： 10.1016/0014-5793(87)81255-3

Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124

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Cited

17 in total

1. Probing the conformation of the fibronectin III1-2 domain by fluorescence resonance energy transfer.

Authors: Nancy W Karuri; Zong Lin; Hays S Rye; Jean E Schwarzbauer
Journal: J Biol Chem Date: 2008-12-08 Impact factor: 5.157

2. Cell traction forces direct fibronectin matrix assembly.

Authors: Christopher A Lemmon; Christopher S Chen; Lewis H Romer
Journal: Biophys J Date: 2009-01 Impact factor: 4.033

Review 3. Fibronectins, their fibrillogenesis, and in vivo functions.

Authors: Jean E Schwarzbauer; Douglas W DeSimone
Journal: Cold Spring Harb Perspect Biol Date: 2011-07-01 Impact factor: 10.005

4. Fibronectin matrix assembly requires distinct contributions from Rho kinases I and -II.

Authors: Atsuko Yoneda; Dmitriy Ushakov; Hinke A B Multhaupt; John R Couchman
Journal: Mol Biol Cell Date: 2006-10-25 Impact factor: 4.138

5. Probing the folded state of fibronectin type III domains in stretched fibrils by measuring buried cysteine accessibility.

Authors: Christopher A Lemmon; Tomoo Ohashi; Harold P Erickson
Journal: J Biol Chem Date: 2011-06-07 Impact factor: 5.157

10. Stretched extracellular matrix proteins turn fouling and are functionally rescued by the chaperones albumin and casein.

Authors: William C Little; Ruth Schwartlander; Michael L Smith; Delphine Gourdon; Viola Vogel
Journal: Nano Lett Date: 2009-12 Impact factor: 11.189

Monoclonal antibody to fibronectin which inhibits extracellular matrix assembly.

1. Probing the conformation of the fibronectin III1-2 domain by fluorescence resonance energy transfer.

2. Cell traction forces direct fibronectin matrix assembly.

Review 3. Fibronectins, their fibrillogenesis, and in vivo functions.

4. Fibronectin matrix assembly requires distinct contributions from Rho kinases I and -II.

5. Probing the folded state of fibronectin type III domains in stretched fibrils by measuring buried cysteine accessibility.

Review 6. Assembly of fibronectin extracellular matrix.

7. Cryptic activity within the Type III₁ domain of fibronectin regulates tissue inflammation and angiogenesis.

8. Identification of a mechanochemical checkpoint and negative feedback loop regulating branching morphogenesis.

9. A novel fibronectin binding site required for fibronectin fibril growth during matrix assembly.

10. Stretched extracellular matrix proteins turn fouling and are functionally rescued by the chaperones albumin and casein.