BACKGROUND/AIMS: To report interocular differences in retinal nerve fibre layer (RNFL), optic nerve head and macular parameters in children using spectral domain optical coherence tomography (SD-OCT). METHODS: This was an observational cross-sectional study including 108 healthy children aged 6-17 years with no ocular abnormality except refractive error. After a comprehensive eye exam and axial length measurement, RNFL, optic nerve and macular thickness measurements were performed using the Cirrus OCT machine. Right and left eyes were compared and interocular differences were computed. Subjects were also divided into two groups based on age (under or over 10 years of age). Main outcome measures were interocular differences and their correlations with age and gender. RESULTS: The study included 108 children, mean age 10.7 ± 3.1 years; significant interocular differences were observed in both macular and RNFL parameters. The macular thickness analysis revealed interocular differences in the outer nasal and outer inferior quadrants, with left eyes displaying larger values. With respect to RNFL parameters, right eyes displayed thicker nasal and temporal quadrants, and inferior clock hours; left eyes had a thicker superior quadrant. The older age group (>10 years) had more pronounced variation in interocular differences compared with the younger group with less mature visual systems. CONCLUSIONS: Normal variation in interocular symmetry exists. Our results can contribute to establishing a standard reference for interocular differences in OCT parameters in children aged 6-17 years using the Cirrus device.
BACKGROUND/AIMS: To report interocular differences in retinal nerve fibre layer (RNFL), optic nerve head and macular parameters in children using spectral domain optical coherence tomography (SD-OCT). METHODS: This was an observational cross-sectional study including 108 healthy children aged 6-17 years with no ocular abnormality except refractive error. After a comprehensive eye exam and axial length measurement, RNFL, optic nerve and macular thickness measurements were performed using the Cirrus OCT machine. Right and left eyes were compared and interocular differences were computed. Subjects were also divided into two groups based on age (under or over 10 years of age). Main outcome measures were interocular differences and their correlations with age and gender. RESULTS: The study included 108 children, mean age 10.7 ± 3.1 years; significant interocular differences were observed in both macular and RNFL parameters. The macular thickness analysis revealed interocular differences in the outer nasal and outer inferior quadrants, with left eyes displaying larger values. With respect to RNFL parameters, right eyes displayed thicker nasal and temporal quadrants, and inferior clock hours; left eyes had a thicker superior quadrant. The older age group (>10 years) had more pronounced variation in interocular differences compared with the younger group with less mature visual systems. CONCLUSIONS: Normal variation in interocular symmetry exists. Our results can contribute to establishing a standard reference for interocular differences in OCT parameters in children aged 6-17 years using the Cirrus device.
Authors: Jie Lu; Hao Zhou; Yingying Shi; James Choe; Mengxi Shen; Liang Wang; Kelly Chen; Qinqin Zhang; William J Feuer; Giovanni Gregori; Philip J Rosenfeld; Ruikang K Wang Journal: Quant Imaging Med Surg Date: 2022-01
Authors: Alicia Muñoz-Gallego; José L Torres-Peña; Martín Rodríguez-Salgado; Ana Ortueta-Olartecoechea; Cristina López-López; Javier De la Cruz; Pilar Tejada-Palacios Journal: Graefes Arch Clin Exp Ophthalmol Date: 2020-08-29 Impact factor: 3.117
Authors: Liangbo L Shen; Shwetha Mangalesh; Brendan McGeehan; Vincent Tai; Neeru Sarin; Mays A El-Dairi; Sharon F Freedman; Maureen G Maguire; Cynthia A Toth Journal: Am J Ophthalmol Date: 2020-09-04 Impact factor: 5.258