Rezaei-Basiri Majid1, Hassan Rezazadeh2, Iraj Asvadi-Kermani3, Mahmud Ghazi-Khansari4, Mehri Golchin5, Mojgan Sarmad5. 1. Research Scholar, Department of Pharmacology and Toxicology, School of Pharmacy, Tabriz University of Medical Sciences , Tabriz-Iran . 2. Associate Professor, Department of Pharmacology and Toxicology, School of Pharmacy, Tabriz University of Medical Sciences , Tabriz-Iran . 3. Professor, Hematology and Oncology Research Center, Tabriz University of Medical Sciences , Tabriz-Iran . 4. Professor, Department of Pharmacology, Faculty of Medicine, Tehran University of Medical Sciences , Tehran-Iran . 5. Hematology and Oncology Research Center, Tabriz University of Medical Sciences , Tabriz-Iran .
Abstract
INTRODUCTION: Vitamin E is an important natural antioxidant, and its most common and biologically active form is α-tocopherol. The antiproliferative effects of alpha-tocopherol have been previously demonstrated. In this study we investigated the effects of vitamin E on urinary epithelial cells and urinary sediments of nursing from oncology hospital. MATERIAL AND METHODS: Sixty-two female nursing personnel from oncology hospital participated in the study. They received orally 200mg of vitamin E per day for two weeks. Also prior to vitamin E and after vitamin E administration, the uroepithelial cells counts and other components of urinary sediments were carried out. RESULTS: There were significant differences in the epithelial cells count and treatment with vitamin E causing significantly more number of epithelial cells and urinary sediments to be excreted in the urine. DISCUSSION: Vitamin E significantly plays an important role on the excretion of uroepithelial cells and urinary sediments. CONCLUSION: In conclusion we propose that use of vitamin E at nontoxic levels would significantly enhance its antioxidative properties, especially among individuals subjected to prophylaxis of occupational hazards.
INTRODUCTION:Vitamin E is an important natural antioxidant, and its most common and biologically active form is α-tocopherol. The antiproliferative effects of alpha-tocopherol have been previously demonstrated. In this study we investigated the effects of vitamin E on urinary epithelial cells and urinary sediments of nursing from oncology hospital. MATERIAL AND METHODS: Sixty-two female nursing personnel from oncology hospital participated in the study. They received orally 200mg of vitamin E per day for two weeks. Also prior to vitamin E and after vitamin E administration, the uroepithelial cells counts and other components of urinary sediments were carried out. RESULTS: There were significant differences in the epithelial cells count and treatment with vitamin E causing significantly more number of epithelial cells and urinary sediments to be excreted in the urine. DISCUSSION: Vitamin E significantly plays an important role on the excretion of uroepithelial cells and urinary sediments. CONCLUSION: In conclusion we propose that use of vitamin E at nontoxic levels would significantly enhance its antioxidative properties, especially among individuals subjected to prophylaxis of occupational hazards.
Entities:
Keywords:
Nursing personnel; Urinary sediments; Uroepithelial cells; Vitamin E
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