S Lin1, H Huang2, X Liu3, Q Li4, A Yang5, Q Zhang6, Z Guo7, Y Chen8. 1. Department of Vascular and Thyroid Surgery, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, No. 107, Yanjiangxi Road, Guangzhou City, Guangdong Province 510120, PR China. Electronic address: linshj@sysucc.org.cn. 2. Department of Head and Neck Surgery, Guangzhou Medical University Cancer Institute and Hospital, No. 78, Hengzhigang Road, Guangzhou City, Guangdong Province 510095, PR China. Electronic address: lussi24@163.com. 3. Department of Head and Neck Surgery, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, No. 651, Dongfengdong Road, Guangzhou City, Guangdong Province 510060, PR China. Electronic address: liuxk@sysucc.org.cn. 4. Department of Head and Neck Surgery, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, No. 651, Dongfengdong Road, Guangzhou City, Guangdong Province 510060, PR China. Electronic address: liql@sysucc.org.cn. 5. Department of Head and Neck Surgery, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, No. 651, Dongfengdong Road, Guangzhou City, Guangdong Province 510060, PR China. Electronic address: yangak@sysucc.org.cn. 6. Department of Head and Neck Surgery, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, No. 651, Dongfengdong Road, Guangzhou City, Guangdong Province 510060, PR China. Electronic address: zhangquan@sysucc.org.cn. 7. Department of Head and Neck Surgery, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, No. 651, Dongfengdong Road, Guangzhou City, Guangdong Province 510060, PR China. Electronic address: guozhum163@126.com. 8. Department of Head and Neck Surgery, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center of Cancer Medicine, No. 651, Dongfengdong Road, Guangzhou City, Guangdong Province 510060, PR China. Electronic address: chenyf@sysucc.org.cn.
Abstract
OBJECTIVE: To evaluate the treatment, prognosis, and complications of differentiated thyroid carcinoma with tracheal invasion. We report our outcomes from a single center using a tracheal sleeve resection. PATIENTS AND METHODS: Retrospective analysis of clinicopathological data on tracheal sleeve resection in patients with thyroid cancer and accompanying tracheal invasion from January 2009 to July 2012. The postoperative complications were analyzed and the literature was reviewed. RESULTS: Nineteen patients with thyroid carcinoma and accompanying tracheal invasion underwent tracheal sleeve resection followed by end-to-end anastomosis. The median survival time was 22 months. Five patients (5/19) developed postoperative complications. The major complications included bilateral recurrent laryngeal nerve paralysis (2 cases), tracheal anastomotic stenosis (1 case), esophageal fistula (2 cases), and anastomotic dehiscence (2 cases). The treatment for these complications included partial posterior cordectomy by CO₂ laser for bilateral recurrent laryngeal nerve paralysis; CO₂ laser treatment followed by postoperative external beam radiotherapy (EBRT) (20 Gy/10 times) for tracheal anastomotic stenosis, femoral anterior dissociative flap to repair esophageal fistula, and a T-tube positioned in the wound in cases of anastomotic dehiscence. CONCLUSIONS: Tracheal sleeve resection remain a safe option with less morbidity and perioperative complications for the management of patients with differentiated thyroid carcinoma accompanied by intratracheal invasion.
OBJECTIVE: To evaluate the treatment, prognosis, and complications of differentiated thyroid carcinoma with tracheal invasion. We report our outcomes from a single center using a tracheal sleeve resection. PATIENTS AND METHODS: Retrospective analysis of clinicopathological data on tracheal sleeve resection in patients with thyroid cancer and accompanying tracheal invasion from January 2009 to July 2012. The postoperative complications were analyzed and the literature was reviewed. RESULTS: Nineteen patients with thyroid carcinoma and accompanying tracheal invasion underwent tracheal sleeve resection followed by end-to-end anastomosis. The median survival time was 22 months. Five patients (5/19) developed postoperative complications. The major complications included bilateral recurrent laryngeal nerve paralysis (2 cases), tracheal anastomotic stenosis (1 case), esophageal fistula (2 cases), and anastomotic dehiscence (2 cases). The treatment for these complications included partial posterior cordectomy by CO₂ laser for bilateral recurrent laryngeal nerve paralysis; CO₂ laser treatment followed by postoperative external beam radiotherapy (EBRT) (20 Gy/10 times) for tracheal anastomotic stenosis, femoral anterior dissociative flap to repair esophageal fistula, and a T-tube positioned in the wound in cases of anastomotic dehiscence. CONCLUSIONS: Tracheal sleeve resection remain a safe option with less morbidity and perioperative complications for the management of patients with differentiated thyroid carcinoma accompanied by intratracheal invasion.
Authors: Vincenzo Pappalardo; Stefano La Rosa; Andrea Imperatori; Nicola Rotolo; Maria Laura Tanda; Andrea Sessa; Lorenzo Dominioni; Gianlorenzo Dionigi Journal: Gland Surg Date: 2016-10
Authors: Cesare Piazza; Davide Lancini; Michele Tomasoni; Anil D'Cruz; Dana M Hartl; Luiz P Kowalski; Gregory W Randolph; Alessandra Rinaldo; Jatin P Shah; Ashok R Shaha; Ricard Simo; Vincent Vander Poorten; Mark Zafereo; Alfio Ferlito Journal: Front Endocrinol (Lausanne) Date: 2021-11-11 Impact factor: 5.555