Mónica Faro1, Naia Sáez-Francàs2, Jesús Castro-Marrero2, Luisa Aliste2, Antonio Collado3, José Alegre2. 1. EAP CAP Terrassa Nord, Consorci Sanitari de Terrassa, Terrassa, Barcelona, España. Electronic address: 34174mfc@comb.cat. 2. Unidad de Fatiga Crónica, Institut de Recerca Vall d'Hebron, Hospital Universitario Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, España. 3. Unidad de Fibromialgia, Hospital Clínic de Barcelona, Barcelona, España.
Abstract
BACKGROUND AND OBJECTIVE: Different studies have showed association of the chronic fatigue syndrome (CFS) with other pathologies, including fibromyalgia (FM). The objective of this study is to analyze whether there are differences in the clinic and in the assessment of fatigue in CFS patients associated or not with FM. PATIENTS AND METHODS: A cross-sectional, single-site observational study was undertaken on a consecutive cases of a register of CFS patients at CFS Unit in Vall d'Hebron Hospital, Barcelona, from January 2008 until March 2011. The variables analyzed were FM comorbidity, sleep and fatigue characteristics and cognitive, neurological and autonomic symptoms. Questionnaires of fatigue impact scale, fatigue strength and impact on quality of life SF-36 were evaluated. RESULTS: We included 980 CFS patients (mean age: 48±9 years; 91% women). Fibromyalgia was present in 528 patients (54%). The level of fatigue (P=.001) and pain (P<.001) was higher in FM patients. Patients with CFS and FM had more prevalence of sleep-related phenomena. The percentage of patients and the degree of severity of cognitive symptoms, neurological and autonomic dysfunction was higher in FM patients (P<.001). FM patients scored higher on the fatigue impact scale (P<.001) and showed worse results in the quality of life questionnaire (P<.001). CONCLUSIONS: FM co-morbidity worse clinical parameters, fatigue and the perception of quality of life in CFS patients.
BACKGROUND AND OBJECTIVE: Different studies have showed association of the chronic fatigue syndrome (CFS) with other pathologies, including fibromyalgia (FM). The objective of this study is to analyze whether there are differences in the clinic and in the assessment of fatigue in CFSpatients associated or not with FM. PATIENTS AND METHODS: A cross-sectional, single-site observational study was undertaken on a consecutive cases of a register of CFS patients at CFS Unit in Vall d'Hebron Hospital, Barcelona, from January 2008 until March 2011. The variables analyzed were FM comorbidity, sleep and fatigue characteristics and cognitive, neurological and autonomic symptoms. Questionnaires of fatigue impact scale, fatigue strength and impact on quality of life SF-36 were evaluated. RESULTS: We included 980 CFS patients (mean age: 48±9 years; 91% women). Fibromyalgia was present in 528 patients (54%). The level of fatigue (P=.001) and pain (P<.001) was higher in FM patients. Patients with CFS and FM had more prevalence of sleep-related phenomena. The percentage of patients and the degree of severity of cognitive symptoms, neurological and autonomic dysfunction was higher in FM patients (P<.001). FM patients scored higher on the fatigue impact scale (P<.001) and showed worse results in the quality of life questionnaire (P<.001). CONCLUSIONS: FM co-morbidity worse clinical parameters, fatigue and the perception of quality of life in CFS patients.
Authors: Luis Nacul; François Jérôme Authier; Carmen Scheibenbogen; Lorenzo Lorusso; Ingrid Bergliot Helland; Jose Alegre Martin; Carmen Adella Sirbu; Anne Marit Mengshoel; Olli Polo; Uta Behrends; Henrik Nielsen; Patricia Grabowski; Slobodan Sekulic; Nuno Sepulveda; Fernando Estévez-López; Pawel Zalewski; Derek F H Pheby; Jesus Castro-Marrero; Giorgos K Sakkas; Enrica Capelli; Ivan Brundsdlund; John Cullinan; Angelika Krumina; Jonas Bergquist; Modra Murovska; Ruud C W Vermuelen; Eliana M Lacerda Journal: Medicina (Kaunas) Date: 2021-05-19 Impact factor: 2.430
Authors: María Dolores Hinchado; Eduardo Otero; María Del Carmen Navarro; Leticia Martín-Cordero; Isabel Gálvez; Eduardo Ortega Journal: J Clin Med Date: 2022-09-28 Impact factor: 4.964