Literature DB >> 24387709

1,2,3-Triazine scaffold as a potent biologically active moiety: a mini review.

Rajeev Kumar, Amar Deep Singh, Jitendra Singh, Hariram Singh, R K Roy, Anurag Chaudhary1.   

Abstract

1,2,3-Triazine is an interesting class of heterocyclic compounds. Various synthetic analogs of 1,2,3-triazine have been prepared and evaluated for many pharmacological activities in different models with desired findings. Some analogs have shown potent pharmacological activity and may be considered as lead molecule for the development of future drugs. This review is an attempt to organize the chemical and pharmacological aspects of 1,2,3-triazine analogs reported till date systematically since 1970.

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Year:  2014        PMID: 24387709     DOI: 10.2174/1389557513666140103111017

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN: 1389-5575            Impact factor:   3.862


  3 in total

1.  Synthesis and anticancer evaluation of some novel pyrimido[5,4-e][1,2,4]triazines and pyrazolo[3,4-d]pyrimidine using DMF-DMA as methylating and cyclizing agent.

Authors:  Samar A El-Kalyoubi
Journal:  Chem Cent J       Date:  2018-05-23       Impact factor: 4.215

2.  Anthra[1,2-d][1,2,3]triazine-4,7,12(3H)-triones as a New Class of Antistaphylococcal Agents: Synthesis and Biological Evaluation.

Authors:  Viktor Zvarych; Maryna Stasevych; Volodymyr Novikov; Eduard Rusanov; Mykhailo Vovk; Piotr Szweda; Katarzyna Grecka; Slawomir Milewski
Journal:  Molecules       Date:  2019-12-13       Impact factor: 4.411

3.  Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)-s-triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades.

Authors:  Ihab Shawish; Assem Barakat; Ali Aldalbahi; Azizah M Malebari; Mohamed S Nafie; Adnan A Bekhit; Amgad Albohy; Alamgir Khan; Zaheer Ul-Haq; Matti Haukka; Beatriz G de la Torre; Fernando Albericio; Ayman El-Faham
Journal:  ACS Omega       Date:  2022-07-07
  3 in total

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