Literature DB >> 2438602

Trigeminal origin of beta-preprotachykinin products in feline pial blood vessels.

K Saito, S Greenberg, M A Moskowitz.   

Abstract

A specific and sensitive radioimmunoassay measured the presence of immunoreactive neurokinin A within feline and human pial arteries. Immunoreactivity exhibited a retention time identical to that of synthetic peptide when acid extracts from feline and human blood vessels were subjected to reverse-phase high-performance liquid chromatography. As shown previously for substance P, levels of immunoreactive neurokinin A decreased significantly in the vessels from the ipsilateral rostral circle of Willis 19-24 days following unilateral trigeminal ganglionectomy. Hence, trigeminal projections to cerebral blood vessels contain both products of beta-preprotachykinin mRNA.

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Year:  1987        PMID： 2438602     DOI： 10.1016/0304-3940(87)90194-7

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  5 in total

1.  Non-NMDA glutamate receptors modulate capsaicin induced c-fos expression within trigeminal nucleus caudalis.

Authors:  D D Mitsikostas; M Sanchez del Rio; C Waeber; Z Huang; F M Cutrer; M A Moskowitz
Journal:  Br J Pharmacol       Date:  1999-06       Impact factor: 8.739

2.  Trigeminovascular fibers increase blood flow in cortical gray matter by axon reflex-like mechanisms during acute severe hypertension or seizures.

Authors:  D E Sakas; M A Moskowitz; E P Wei; H A Kontos; M Kano; C S Ogilvy
Journal:  Proc Natl Acad Sci U S A       Date:  1989-02       Impact factor: 11.205

3.  The antimigraine drug, sumatriptan (GR43175), selectively blocks neurogenic plasma extravasation from blood vessels in dura mater.

Authors:  M G Buzzi; M A Moskowitz
Journal:  Br J Pharmacol       Date:  1990-01       Impact factor: 8.739

4.  The head and neck discomfort of autonomic failure: an unrecognized aetiology of headache.

Authors:  D Robertson; D W Kincaid; V Haile; R M Robertson
Journal:  Clin Auton Res       Date:  1994-06       Impact factor: 4.435

5.  Neocortical spreading depression provokes the expression of c-fos protein-like immunoreactivity within trigeminal nucleus caudalis via trigeminovascular mechanisms.

Authors:  M A Moskowitz; K Nozaki; R P Kraig
Journal:  J Neurosci       Date:  1993-03       Impact factor: 6.167
  5 in total

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