Literature DB >> 24385199

Mortality deceleration and mortality selection: three unexpected implications of a simple model.

Elizabeth Wrigley-Field1.   

Abstract

Unobserved heterogeneity in mortality risk is pervasive and consequential. Mortality deceleration-the slowing of mortality's rise with age-has been considered an important window into heterogeneity that otherwise might be impossible to explore. In this article, I argue that deceleration patterns may reveal surprisingly little about the heterogeneity that putatively produces them. I show that even in a very simple model-one that is composed of just two subpopulations with Gompertz mortality-(1) aggregate mortality can decelerate even while a majority of the cohort is frail; (2) multiple decelerations are possible; and (3) mortality selection can produce acceleration as well as deceleration. Simulations show that these patterns are plausible in model cohorts that in the aggregate resemble cohorts in the Human Mortality Database. I argue that these results challenge some conventional heuristics for understanding the relationship between selection and deceleration; undermine certain inferences from deceleration timing to patterns of social inequality; and imply that standard parametric models, assumed to plateau at most once, may sometimes badly misestimate deceleration timing-even by decades.

Entities:  

Mesh:

Year:  2014        PMID: 24385199      PMCID: PMC4559263          DOI: 10.1007/s13524-013-0256-7

Source DB:  PubMed          Journal:  Demography        ISSN: 0070-3370


  34 in total

1.  Measuring the compression of mortality.

Authors:  V Kannisto
Journal:  Demogr Res       Date:  2000-09-12

2.  Lifelong heterogeneity in fecundity is insufficient to explain late-life fecundity plateaus in Drosophila melanogaster.

Authors:  Casandra L Rauser; Yasmine Abdel-Aal; Jonathan A Shieh; Christine W Suen; Laurence D Mueller; Michael R Rose
Journal:  Exp Gerontol       Date:  2005 Aug-Sep       Impact factor: 4.032

3.  Reproducing inequalities: luck, wallets, and the enduring effects of childhood health.

Authors:  Alberto Palloni
Journal:  Demography       Date:  2006-11

4.  The impact of heterogeneity in individual frailty on the dynamics of mortality.

Authors:  J W Vaupel; K G Manton; E Stallard
Journal:  Demography       Date:  1979-08

5.  Admissible mixing distributions for a general class of mixture survival models with known asymptotics.

Authors:  Trifon I Missov; Maxim Finkelstein
Journal:  Theor Popul Biol       Date:  2011-05-10       Impact factor: 1.570

6.  The significance of education for mortality compression in the United States.

Authors:  Dustin C Brown; Mark D Hayward; Jennifer Karas Montez; Robert A Hummer; Chi-Tsun Chiu; Mira M Hidajat
Journal:  Demography       Date:  2012-08

7.  The implications of increased survivorship for mortality variation in aging populations.

Authors:  Michal Engelman; Vladimir Canudas-Romo; Emily M Agree
Journal:  Popul Dev Rev       Date:  2010

8.  Cumulative index of health deficiencies as a characteristic of long life.

Authors:  Alexander M Kulminski; Svetlana V Ukraintseva; Igor V Akushevich; Konstantin G Arbeev; Anatoli I Yashin
Journal:  J Am Geriatr Soc       Date:  2007-06       Impact factor: 5.562

9.  Slowing of age-specific mortality rates in Drosophila melanogaster.

Authors:  H H Fukui; L Xiu; J W Curtsinger
Journal:  Exp Gerontol       Date:  1993 Nov-Dec       Impact factor: 4.032

10.  Scarring and mortality selection among Civil War POWs: a long-term mortality, morbidity, and socioeconomic follow-up.

Authors:  Dora L Costa
Journal:  Demography       Date:  2012-11
View more
  8 in total

1.  On the beginning of mortality acceleration.

Authors:  Giambattista Salinari; Gustavo De Santis
Journal:  Demography       Date:  2015-02

2.  A simulation study of the role of cohort forces in mortality patterns.

Authors:  Hui Zheng; Siwei Cheng
Journal:  Biodemography Soc Biol       Date:  2018 Jul-Sep

3.  Robust Respondents and Lost Limitations: The Implications of Nonrandom Missingness for the Estimation of Health Trajectories.

Authors:  Heide Jackson; Michal Engelman; Karen Bandeen-Roche
Journal:  J Aging Health       Date:  2017-12-14

4.  The Methuselah Effect: The Pernicious Impact of Unreported Deaths on Old-Age Mortality Estimates.

Authors:  Dan A Black; Yu-Chieh Hsu; Seth G Sanders; Lynne Steuerle Schofield; Lowell J Taylor
Journal:  Demography       Date:  2017-12

5.  Multidimensional Mortality Selection: Why Individual Dimensions of Frailty Don't Act Like Frailty.

Authors:  Elizabeth Wrigley-Field
Journal:  Demography       Date:  2020-04

6.  Detecting the Effects of Early-Life Exposures: Why Fecundity Matters.

Authors:  Jenna Nobles; Amar Hamoudi
Journal:  Popul Res Policy Rev       Date:  2019-11-26

7.  On the heterogeneity of human populations as reflected by mortality dynamics.

Authors:  Demetris Avraam; Séverine Arnold; Olga Vasieva; Bakhtier Vasiev
Journal:  Aging (Albany NY)       Date:  2016-11-22       Impact factor: 5.682

8.  Urinary markers of oxidative stress respond to infection and late-life in wild chimpanzees.

Authors:  Nicole Thompson González; Emily Otali; Zarin Machanda; Martin N Muller; Richard Wrangham; Melissa Emery Thompson
Journal:  PLoS One       Date:  2020-09-11       Impact factor: 3.752

  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.