Literature DB >> 24384772

The challenge of pancreatic cancer therapy and novel treatment strategy using engineered mesenchymal stem cells.

M R Moniri1, L-J Dai2, G L Warnock1.   

Abstract

Mesenchymal stem cells (MSCs) have attracted significant attention in cancer research as a result of their accessibility, tumor-oriented homing capacity, and the feasibility of auto-transplantation. This review provides a comprehensive overview of current challenges in pancreatic cancer therapy, and we propose a novel strategy for using MSCs as means of delivering anticancer genes to the site of pancreas. We aim to provide a practical platform for the development of MSC-based therapy for pancreatic cancer.

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Year:  2014        PMID： 24384772     DOI： 10.1038/cgt.2013.83

Source DB:  PubMed          Journal:  Cancer Gene Ther        ISSN： 0929-1903            Impact factor:   5.987


  189 in total

1.  STRO-1, HOP-26 (CD63), CD49a and SB-10 (CD166) as markers of primitive human marrow stromal cells and their more differentiated progeny: a comparative investigation in vitro.

Authors:  Karina Stewart; Peter Monk; Susan Walsh; Carolyn M Jefferiss; Julie Letchford; Jon N Beresford
Journal:  Cell Tissue Res       Date:  2003-07-22       Impact factor: 5.249

2.  Human mesenchymal stem cells derived from bone marrow display a better chondrogenic differentiation compared with other sources.

Authors:  M E Bernardo; J A M Emons; M Karperien; A J Nauta; R Willemze; H Roelofs; S Romeo; A Marchini; G A Rappold; S Vukicevic; F Locatelli; W E Fibbe
Journal:  Connect Tissue Res       Date:  2007       Impact factor: 3.417

Review 3.  Gene therapy developments for pancreatic cancer.

Authors:  Madhumita Bhattacharyya; Nick R Lemoine
Journal:  Best Pract Res Clin Gastroenterol       Date:  2006-04       Impact factor: 3.043

4.  Outgrowth of a transformed cell population derived from normal human BM mesenchymal stem cell culture.

Authors:  Y Wang; D L Huso; J Harrington; J Kellner; D K Jeong; J Turney; I K McNiece
Journal:  Cytotherapy       Date:  2005       Impact factor: 5.414

Review 5.  PTEN mutation: many birds with one stone in tumorigenesis.

Authors:  Weijin Liu; Yonggang Zhou; Sven N Reske; Changxian Shen
Journal:  Anticancer Res       Date:  2008 Nov-Dec       Impact factor: 2.480

6.  Up-regulation of Wnt-1 and beta-catenin production in patients with advanced metastatic prostate carcinoma: potential pathogenetic and prognostic implications.

Authors:  Gaoping Chen; Nicholas Shukeir; Anil Potti; Kanishka Sircar; Armen Aprikian; David Goltzman; Shafaat A Rabbani
Journal:  Cancer       Date:  2004-09-15       Impact factor: 6.860

7.  The epithelial mesenchymal transition confers resistance to the apoptotic effects of transforming growth factor Beta in fetal rat hepatocytes.

Authors:  Francisco Valdés; Alberto M Alvarez; Annamaria Locascio; Sonia Vega; Blanca Herrera; Margarita Fernández; Manuel Benito; M Angela Nieto; Isabel Fabregat
Journal:  Mol Cancer Res       Date:  2002-11       Impact factor: 5.852

8.  Monocyte chemotactic protein-1 secreted by primary breast tumors stimulates migration of mesenchymal stem cells.

Authors:  R M Dwyer; S M Potter-Beirne; K A Harrington; A J Lowery; E Hennessy; J M Murphy; F P Barry; T O'Brien; M J Kerin
Journal:  Clin Cancer Res       Date:  2007-09-01       Impact factor: 12.531

Review 9.  Stem cells as vectors for antitumour therapy.

Authors:  Michael R Loebinger; Sam M Janes
Journal:  Thorax       Date:  2010-04       Impact factor: 9.139

10.  Mesenchymal stem cells.

Authors:  A I Caplan
Journal:  J Orthop Res       Date:  1991-09       Impact factor: 3.494
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  14 in total

Review 1.  New targeted therapies in pancreatic cancer.

Authors:  Andrada Seicean; Livia Petrusel; Radu Seicean
Journal:  World J Gastroenterol       Date:  2015-05-28       Impact factor: 5.742

2.  A concise review on the current understanding of pancreatic cancer stem cells.

Authors:  Arokia Priyanka Vaz; Moorthy P Ponnusamy; Parthasarathy Seshacharyulu; Surinder K Batra
Journal:  J Cancer Stem Cell Res       Date:  2014

Review 3.  Viro-immune therapy: A new strategy for treatment of pancreatic cancer.

Authors:  Andrea Marie Ibrahim; Yao-He Wang
Journal:  World J Gastroenterol       Date:  2016-01-14       Impact factor: 5.742

Review 4.  Emerging roles of microRNAs in pancreatic cancer diagnosis, therapy and prognosis (Review).

Authors:  Ramadevi Subramani; Laxman Gangwani; Sushmita Bose Nandy; Arunkumar Arumugam; Munmun Chattopadhyay; Rajkumar Lakshmanaswamy
Journal:  Int J Oncol       Date:  2015-08-21       Impact factor: 5.650

5.  Paracrine factors from adipose-mesenchymal stem cells enhance metastatic capacity through Wnt signaling pathway in a colon cancer cell co-culture model.

Authors:  Dongmei Chen; Shudan Liu; Huiming Ma; Xueyun Liang; Haibin Ma; Xiurui Yan; Bao Yang; Jun Wei; Xiaoming Liu
Journal:  Cancer Cell Int       Date:  2015-04-18       Impact factor: 5.722

6.  cDNA microarray analysis of the effect of cantharidin on DNA damage, cell cycle and apoptosis-associated gene expression in NCI-H460 human lung cancer cells in vitro.

Authors:  Te-Chun Hsia; Chien-Chih Yu; Shu-Chun Hsu; Nou-Ying Tang; Hsu-Feng Lu; Chun-Shu Yu; Shin-Hwar Wu; Jaung-Geng Lin; Jing-Gung Chung
Journal:  Mol Med Rep       Date:  2015-03-24       Impact factor: 2.952

7.  Clinical data combined with radiological imaging improves the accuracy of TNM staging of pancreatic body and tail adenocarcinoma.

Authors:  Wei Xu; Bo Jiang; Xinmin Yin
Journal:  Patient Prefer Adherence       Date:  2017-10-04       Impact factor: 2.711

8.  Secretion of interleukin-6 by bone marrow mesenchymal stem cells promotes metastasis in hepatocellular carcinoma.

Authors:  Fei Mi; Liansheng Gong
Journal:  Biosci Rep       Date:  2017-07-21       Impact factor: 3.840

Review 9.  Molecular and Cellular Interactions of Allogenic and Autologus Mesenchymal Stem Cells with Innate and Acquired Immunity and Their Role in Regenerative Medicine.

Authors:  Roghayeh Hosseinikia; Mohammad Reza Nikbakht; Ali Asghar Moghaddam; Ahmad Tajehmiri; Mahboobe Hosseinikia; Farhad Oubari; Mahin Nikougoftar Zarif; Yahya Pasdar; Kamran Mansouri
Journal:  Int J Hematol Oncol Stem Cell Res       Date:  2017-01-01

10.  ROR functions as a ceRNA to regulate Nanog expression by sponging miR-145 and predicts poor prognosis in pancreatic cancer.

Authors:  Song Gao; Peng Wang; Yongqiang Hua; Hao Xi; Zhiqiang Meng; Te Liu; Zhen Chen; Luming Liu
Journal:  Oncotarget       Date:  2016-01-12
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