Literature DB >> 24384694

EFdA, a reverse transcriptase inhibitor, potently blocks HIV-1 ex vivo infection of Langerhans cells within epithelium.

Takamitsu Matsuzawa1, Tatsuyoshi Kawamura2, Youichi Ogawa1, Kenji Maeda3, Hirotomo Nakata4, Kohji Moriishi5, Yoshio Koyanagi6, Hiroyuki Gatanaga7, Shinji Shimada1, Hiroaki Mitsuya8.   

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Year:  2013        PMID: 24384694     DOI: 10.1038/jid.2013.467

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN: 0022-202X            Impact factor:   8.551


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  15 in total

Review 1.  Microbicides and other topical strategies to prevent vaginal transmission of HIV.

Authors:  Michael M Lederman; Robin E Offord; Oliver Hartley
Journal:  Nat Rev Immunol       Date:  2006-05       Impact factor: 53.106

2.  Effectiveness and safety of tenofovir gel, an antiretroviral microbicide, for the prevention of HIV infection in women.

Authors:  Quarraisha Abdool Karim; Salim S Abdool Karim; Janet A Frohlich; Anneke C Grobler; Cheryl Baxter; Leila E Mansoor; Ayesha B M Kharsany; Sengeziwe Sibeko; Koleka P Mlisana; Zaheen Omar; Tanuja N Gengiah; Silvia Maarschalk; Natasha Arulappan; Mukelisiwe Mlotshwa; Lynn Morris; Douglas Taylor
Journal:  Science       Date:  2010-07-19       Impact factor: 47.728

3.  2'-deoxy-4'-C-ethynyl-2-fluoroadenosine, a nucleoside reverse transcriptase inhibitor, is highly potent against all human immunodeficiency viruses type 1 and has low toxicity.

Authors:  Hiroshi Ohrui
Journal:  Chem Rec       Date:  2006       Impact factor: 6.771

4.  2'-deoxy-4'-C-ethynyl-2-fluoroadenosine: a nucleoside reverse transcriptase inhibitor with highly potent activity against wide spectrum of HIV-1 strains, favorable toxic profiles, and stability in plasma.

Authors:  Hiroshi Ohrui; Satoru Kohgo; Hiroyuki Hayakawa; Eiichi Kodama; Masao Matsuoka; Tomohiro Nakata; Hiroaki Mitsuya
Journal:  Nucleosides Nucleotides Nucleic Acids       Date:  2007       Impact factor: 1.381

5.  Within 1 h, HIV-1 uses viral synapses to enter efficiently the inner, but not outer, foreskin mucosa and engages Langerhans-T cell conjugates.

Authors:  Y Ganor; Z Zhou; D Tudor; A Schmitt; M-C Vacher-Lavenu; L Gibault; N Thiounn; J Tomasini; J-P Wolf; M Bomsel
Journal:  Mucosal Immunol       Date:  2010-06-23       Impact factor: 7.313

6.  Mechanism of inhibition of HIV-1 reverse transcriptase by 4'-Ethynyl-2-fluoro-2'-deoxyadenosine triphosphate, a translocation-defective reverse transcriptase inhibitor.

Authors:  Eleftherios Michailidis; Bruno Marchand; Eiichi N Kodama; Kamlendra Singh; Masao Matsuoka; Karen A Kirby; Emily M Ryan; Ali M Sawani; Eva Nagy; Noriyuki Ashida; Hiroaki Mitsuya; Michael A Parniak; Stefan G Sarafianos
Journal:  J Biol Chem       Date:  2009-12-18       Impact factor: 5.157

7.  In vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicide.

Authors:  Lisa C Rohan; Bernard J Moncla; Ratiya Pamela Kunjara Na Ayudhya; Marilyn Cost; Yunda Huang; Fang Gai; Nicole Billitto; J D Lynam; Kara Pryke; Phillip Graebing; Nicole Hopkins; James F Rooney; David Friend; Charlene S Dezzutti
Journal:  PLoS One       Date:  2010-02-19       Impact factor: 3.240

8.  Genotypic and phenotypic characterization of HIV-1 patients with primary infection.

Authors:  T Zhu; H Mo; N Wang; D S Nam; Y Cao; R A Koup; D D Ho
Journal:  Science       Date:  1993-08-27       Impact factor: 47.728

9.  Activity against human immunodeficiency virus type 1, intracellular metabolism, and effects on human DNA polymerases of 4'-ethynyl-2-fluoro-2'-deoxyadenosine.

Authors:  Hirotomo Nakata; Masayuki Amano; Yasuhiro Koh; Eiichi Kodama; Guangwei Yang; Christopher M Bailey; Satoru Kohgo; Hiroyuki Hayakawa; Masao Matsuoka; Karen S Anderson; Yung-Chi Cheng; Hiroaki Mitsuya
Journal:  Antimicrob Agents Chemother       Date:  2007-06-04       Impact factor: 5.191

10.  HIV-1 efficient entry in inner foreskin is mediated by elevated CCL5/RANTES that recruits T cells and fuels conjugate formation with Langerhans cells.

Authors:  Zhicheng Zhou; Nicolas Barry de Longchamps; Alain Schmitt; Marc Zerbib; Marie-Cécile Vacher-Lavenu; Morgane Bomsel; Yonatan Ganor
Journal:  PLoS Pathog       Date:  2011-06-30       Impact factor: 6.823

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  1 in total

Review 1.  The role of human dendritic cells in HIV-1 infection.

Authors:  Zahra Ahmed; Tatsuyoshi Kawamura; Shinji Shimada; Vincent Piguet
Journal:  J Invest Dermatol       Date:  2014-11-19       Impact factor: 8.551

  1 in total

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