Literature DB >> 24384115

An update on Parkinson's disease: improving patient outcomes.

Daniel Kremens1, Robert A Hauser2, E Ray Dorsey3.   

Abstract

Neurologists are faced with many challenges in caring for patients with Parkinson's disease (PD). This chronic, long-term illness that affects at least one million people in the United States requires a coordinated healthcare partnership between the physician and the patient. The importance of early diagnosis is essential to delaying disease progression and early diagnosis and intervention may be aided by recent advances in biomarkers, genomics, and imaging. A misdiagnosis or late diagnosis will lead to deteriorating patient health. Additionally, physicians should incorporate current guidelines into their treatment strategies, and awareness of the reasoning behind these guidelines is critical for appropriate use. Physicians should be up to date on identifying the most appropriate therapies based on emerging science and disease staging, and should implement patient education into their practice. Due to limitations for currently available therapies, adjunctive therapies may lead to improved outcomes in patients with PD. The use of multiple therapies can improve myriad symptoms, more so than a monotherapy. Knowledge of these therapies is critical to achieving best outcomes in patients with PD. This webcast will discuss the current challenges with PD clinical practice, clinical features of PD, the impact of treatment, future treatments for PD and improving patient outcomes.
Copyright © 2014. Published by Elsevier Inc.

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Year:  2014        PMID: 24384115     DOI: 10.1016/j.amjmed.2013.06.016

Source DB:  PubMed          Journal:  Am J Med        ISSN: 0002-9343            Impact factor:   4.965


  8 in total

1.  Neuroprotective effects of Eucommia ulmoides Oliv. and its bioactive constituent work via ameliorating the ubiquitin-proteasome system.

Authors:  Hong Guo; Fang Shi; Meijiao Li; Qingqing Liu; Bin Yu; Limin Hu
Journal:  BMC Complement Altern Med       Date:  2015-05-21       Impact factor: 3.659

2.  Alpha-synuclein in cutaneous small nerve fibers.

Authors:  Timo Siepmann; Ben Min-Woo Illigens; Kristian Barlinn
Journal:  Neuropsychiatr Dis Treat       Date:  2016-10-25       Impact factor: 2.570

3.  Cutaneous Autonomic Pilomotor Testing to Unveil the Role of Neuropathy Progression in Early Parkinson's Disease (CAPTURE PD): Protocol for a Multicenter Study.

Authors:  Timo Siepmann; Alexandra Pintér; Sylvia J Buchmann; Leonie Stibal; Martin Arndt; Anne Sophie Kubasch; Marie Luise Kubasch; Ana Isabel Penzlin; Elka Frenz; Wagner Zago; Tamás Horváth; Szabolcs Szatmári; Dániel Bereczki; Annamária Takáts; Tjalf Ziemssen; Axel Lipp; Roy Freeman; Heinz Reichmann; Kristian Barlinn; Ben Min-Woo Illigens
Journal:  Front Neurol       Date:  2017-05-26       Impact factor: 4.003

4.  Effect on Gait Speed, Balance, Motor Symptom Rating, and Quality of Life in Those with Stage I Parkinson's Disease Utilizing LSVT BIG®.

Authors:  Beth Millage; Erin Vesey; Marsha Finkelstein; Mattie Anheluk
Journal:  Rehabil Res Pract       Date:  2017-02-26

5.  Single Sensor Gait Analysis to Detect Diabetic Peripheral Neuropathy: A Proof of Principle Study.

Authors:  Patrick Esser; Johnny Collett; Kevin Maynard; Dax Steins; Angela Hillier; Jodie Buckingham; Garry D Tan; Laurie King; Helen Dawes
Journal:  Diabetes Metab J       Date:  2018-02       Impact factor: 5.376

6.  Fluoxetine-mediated inhibition of endoplasmic reticulum stress is involved in the neuroprotective effects of Parkinson's disease.

Authors:  Tao Peng; Xiaoyan Liu; Jingtao Wang; Yu Liu; Zhenqiang Fu; Xingrong Ma; Junmin Li; Guifang Sun; Yangfei Ji; Jingjing Lu; Wencui Wan; Hong Lu
Journal:  Aging (Albany NY)       Date:  2018-12-24       Impact factor: 5.682

7.  Patient perceptions and knowledge of Parkinson's disease and treatment (KnowPD).

Authors:  Meagen R Salinas; Elizabeth J Chambers; Travis Ho; Pravin Khemani; DaiWai M Olson; Sonja Stutzman; Shilpa Chitnis
Journal:  Clin Park Relat Disord       Date:  2020-01-16

Review 8.  Should Skin Biopsies Be Performed in Patients Suspected of Having Parkinson's Disease?

Authors:  Timo Siepmann; Ana Isabel Penzlin; Ben Min-Woo Illigens; Heinz Reichmann
Journal:  Parkinsons Dis       Date:  2017-10-30
  8 in total

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