Literature DB >> 24382648

Structural basis for regulation of ribosomal RNA 2'-o-methylation.

Martin Hengesbach1, Harald Schwalbe.   

Abstract

Methods that interrogate different, yet overlapping structural-size ranges were integrated to gain high-resolution information on the Pyrococcus furiosus box C/D ribonucleoprotein complex. The new structure shows how 2'-O-methylation of RNA substrates through four active methyltransferases occurs in a strictly sequential manner.
Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  2′-O-methylation; NMR spectroscopy; RNA modification; ribosome biogenesis; small-angle neutron scattering

Mesh：

Substances：

Year:  2014        PMID： 24382648     DOI： 10.1002/anie.201309604

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  4 in total

1.  NmSEER V2.0: a prediction tool for 2'-O-methylation sites based on random forest and multi-encoding combination.

Authors:  Yiran Zhou; Qinghua Cui; Yuan Zhou
Journal:  BMC Bioinformatics       Date:  2019-12-24       Impact factor: 3.169

2.  Assignment of 2'-O-methyltransferases to modification sites on the mammalian mitochondrial large subunit 16 S ribosomal RNA (rRNA).

Authors:  Ken-Wing Lee; Daniel F Bogenhagen
Journal:  J Biol Chem       Date:  2014-07-29       Impact factor: 5.157

3.  DeepOMe: A Web Server for the Prediction of 2'-O-Me Sites Based on the Hybrid CNN and BLSTM Architecture.

Authors:  Hongyu Li; Li Chen; Zaoli Huang; Xiaotong Luo; Huiqin Li; Jian Ren; Yubin Xie
Journal:  Front Cell Dev Biol       Date:  2021-05-14

4.  High-throughput single-base resolution mapping of RNA 2΄-O-methylated residues.

Authors:  Danny Incarnato; Francesca Anselmi; Edoardo Morandi; Francesco Neri; Mara Maldotti; Stefania Rapelli; Caterina Parlato; Giulia Basile; Salvatore Oliviero
Journal:  Nucleic Acids Res       Date:  2017-02-17       Impact factor: 16.971
  4 in total

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