Literature DB >> 24382636

Cholesterol's aliphatic side chain modulates membrane properties.

Holger A Scheidt1, Thomas Meyer, Jörg Nikolaus, Dong Jae Baek, Ivan Haralampiev, Lars Thomas, Robert Bittman, Peter Müller, Andreas Herrmann, Daniel Huster.   

Abstract

The influence of cholesterol's alkyl side chain on membrane properties was studied using a series of synthetic cholesterol derivatives without a side chain or with a branched side chain consisting of 5 to 14 carbon atoms. Cholesterol's side chain is crucial for all membrane properties investigated and therefore essential for the membrane properties of eukaryotic cells.
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  diffusion; domain formation; lipids; membranes; permeability

Mesh：

Substances：

Year:  2013        PMID： 24382636      PMCID： PMC4011182          DOI： 10.1002/anie.201306753

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  36 in total

1.  Temperature-dependent phase behavior and protein partitioning in giant plasma membrane vesicles.

Authors:  S A Johnson; B M Stinson; M S Go; L M Carmona; J I Reminick; X Fang; T Baumgart
Journal:  Biochim Biophys Acta       Date:  2010-03-15

2.  Water permeability of polyunsaturated lipid membranes measured by 17O NMR.

Authors:  D Huster; A J Jin; K Arnold; K Gawrisch
Journal:  Biophys J       Date:  1997-08       Impact factor: 4.033

3.  Elucidating membrane structure and protein behavior using giant plasma membrane vesicles.

Authors:  Erdinc Sezgin; Hermann-Josef Kaiser; Tobias Baumgart; Petra Schwille; Kai Simons; Ilya Levental
Journal:  Nat Protoc       Date:  2012-05-03       Impact factor: 13.491

4.  Effect of sterol structure on the bending rigidity of lipid membranes: A (2)H NMR transverse relaxation study.

Authors:  Greger Orädd; Vahid Shahedi; Göran Lindblom
Journal:  Biochim Biophys Acta       Date:  2009-06-30

Review 5.  Functions of lipid rafts in biological membranes.

Authors:  D A Brown; E London
Journal:  Annu Rev Cell Dev Biol       Date:  1998       Impact factor: 13.827

6.  Influence of docosahexaenoic acid and cholesterol on lateral lipid organization in phospholipid mixtures.

Authors:  D Huster; K Arnold; K Gawrisch
Journal:  Biochemistry       Date:  1998-12-08       Impact factor: 3.162

7.  Spectroscopic studies of specifically deuterium labeled membrane systems. Nuclear magnetic resonance investigation of the effects of cholesterol in model systems.

Authors:  E Oldfield; M Meadows; D Rice; R Jacobs
Journal:  Biochemistry       Date:  1978-07-11       Impact factor: 3.162

8.  Desmosterol may replace cholesterol in lipid membranes.

Authors:  Daniel Huster; Holger A Scheidt; Klaus Arnold; Andreas Herrmann; Peter Müller
Journal:  Biophys J       Date:  2004-12-13       Impact factor: 4.033

9.  The potential of fluorescent and spin-labeled steroid analogs to mimic natural cholesterol.

Authors:  Holger A Scheidt; Peter Muller; Andreas Herrmann; Daniel Huster
Journal:  J Biol Chem       Date:  2003-08-28       Impact factor: 5.157

10.  Raftlike mixtures of sphingomyelin and cholesterol investigated by solid-state 2H NMR spectroscopy.

Authors:  Tim Bartels; Ravi S Lankalapalli; Robert Bittman; Klaus Beyer; Michael F Brown
Journal:  J Am Chem Soc       Date:  2008-10-08       Impact factor: 15.419
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  20 in total

1.  The orientation and dynamics of estradiol and estradiol oleate in lipid membranes and HDL disc models.

Authors:  Alexander Vogel; Holger A Scheidt; Scott E Feller; Jari Metso; Robert M Badeau; Matti J Tikkanen; Kristiina Wähälä; Matti Jauhiainen; Daniel Huster
Journal:  Biophys J       Date:  2014-07-01       Impact factor: 4.033

2.  The dynamics of the G protein-coupled neuropeptide Y2 receptor in monounsaturated membranes investigated by solid-state NMR spectroscopy.

Authors:  Lars Thomas; Julian Kahr; Peter Schmidt; Ulrike Krug; Holger A Scheidt; Daniel Huster
Journal:  J Biomol NMR       Date:  2015-01-06       Impact factor: 2.835

3.  The Affinity of Sterols for Different Phospholipid Classes and Its Impact on Lateral Segregation.

Authors:  Thomas K M Nyholm; Shishir Jaikishan; Oskar Engberg; Victor Hautala; J Peter Slotte
Journal:  Biophys J       Date:  2018-12-06       Impact factor: 4.033

4.  Domain Stability in Biomimetic Membranes Driven by Lipid Polyunsaturation.

Authors:  Xubo Lin; Joseph H Lorent; Allison D Skinkle; Kandice R Levental; M Neal Waxham; Alemayehu A Gorfe; Ilya Levental
Journal:  J Phys Chem B       Date:  2016-11-10       Impact factor: 2.991

Review 5.  Cholesterol-induced suppression of membrane elastic fluctuations at the atomistic level.

Authors:  Trivikram R Molugu; Michael F Brown
Journal:  Chem Phys Lipids       Date:  2016-05-03       Impact factor: 3.329

6.  The aliphatic chain of cholesterol modulates bilayer interleaflet coupling and domain registration.

Authors:  Xubo Lin; Siya Zhang; Hui Ding; Ilya Levental; Alemayehu A Gorfe
Journal:  FEBS Lett       Date:  2016-09-22       Impact factor: 4.124

7.  Lipid Interactions and Organization in Complex Bilayer Membranes.

Authors:  Oskar Engberg; Tomokazu Yasuda; Victor Hautala; Nobuaki Matsumori; Thomas K M Nyholm; Michio Murata; J Peter Slotte
Journal:  Biophys J       Date:  2016-04-12       Impact factor: 4.033

8.  Bexarotene Binds to the Amyloid Precursor Protein Transmembrane Domain, Alters Its α-Helical Conformation, and Inhibits γ-Secretase Nonselectively in Liposomes.

Authors:  Frits Kamp; Holger A Scheidt; Edith Winkler; Gabriele Basset; Hannes Heinel; James M Hutchison; Loren M LaPointe; Charles R Sanders; Harald Steiner; Daniel Huster
Journal:  ACS Chem Neurosci       Date:  2018-05-11       Impact factor: 4.418

9.  Vesicle Leakage Reflects the Target Selectivity of Antimicrobial Lipopeptides from Bacillus subtilis.

Authors:  Sebastian Fiedler; Heiko Heerklotz
Journal:  Biophys J       Date:  2015-11-17       Impact factor: 4.033

10.  Design, Synthesis, and Evaluation of a Luminescent Cholesterol Mimic.

Authors:  Emily M Work; Guillermo Ferraudi; Luke Kiefer; Gang Liu; Michael Grigalunas; Atul Bhardwaj; Rasmin Kaur; Janel M Dempsey; Daniel Wüstner; Paul Helquist; Olaf Wiest
Journal:  J Org Chem       Date:  2020-12-28       Impact factor: 4.354
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