Literature DB >> 24382579

Metal-free cascade radical cyclization of 1,6-enynes with aldehydes.

Jian-Yi Luo1, Hui-Liang Hua, Zi-Sheng Chen, Zhao-Zhao Zhou, Yan-Fang Yang, Ping-Xin Zhou, Yu-Tao He, Xue-Yuan Liu, Yong-Min Liang.   

Abstract

A new and efficient metal-free cascade cyclization of 1,6-enynes with aldehydes is developed for the synthesis of tricyclic fluorene derivatives. The reaction involves a radical process and one C(sp(2))-C(sp(2)) and two C(sp(2))-C(sp(3)) bonds are formed simultaneously in one pot by using PivOH and TBHP.

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Year:  2014        PMID： 24382579     DOI： 10.1039/c3cc48339h

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  Characterization of novel perylene diimides containing aromatic amino acid side chains.

Authors:  Mohammed J Farooqi; Mark A Penick; Jessica Burch; George R Negrete; Lorenzo Brancaleon
Journal:  Spectrochim Acta A Mol Biomol Spectrosc       Date:  2015-08-16       Impact factor: 4.098

2.  Construction of Polycyclic γ-Lactams and Related Heterocycles via Electron Catalysis.

Authors:  Jun Xuan; Constantin G Daniliuc; Armido Studer
Journal:  Org Lett       Date:  2016-11-29       Impact factor: 6.005

3.  Intermolecular oxidative decarbonylative [2 + 2 + 2] carbocyclization of N-(2-ethynylaryl)acrylamides with tertiary and secondary alkyl aldehydes involving C(sp3)-H functionalization.

Authors:  Yang Li; Gao-Hui Pan; Ming Hu; Bang Liu; Ren-Jie Song; Jin-Heng Li
Journal:  Chem Sci       Date:  2016-07-21       Impact factor: 9.825

4.  Copper-catalyzed cascade annulation of unsaturated α-bromocarbonyls with enynals: a facile access to ketones from aldehydes.

Authors:  Chao Che; Qianwen Huang; Hanliang Zheng; Gangguo Zhu
Journal:  Chem Sci       Date:  2016-03-04       Impact factor: 9.825
  4 in total

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